Pharmacology and Therapeutics
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Glucocorticoid resistance of migration and gene expression in a daughter MDA-MB-231 breast tumour cell line selected for high metastatic potential
(NATURE PUBLISHING GROUP, 2017-03-06)Glucocorticoids are commonly used to prevent chemotherapy-induced nausea and vomiting despite a lack of understanding of their direct effect on cancer progression. Recent studies suggest that glucocorticoids inhibit cancer ... -
Translational Pharmacology
(FRONTIERS MEDIA SA, 2017-01-19) -
The fibrogenic actions of lung fibroblast-derived urokinase: a potential drug target in IPF
(NATURE PUBLISHING GROUP, 2017-01-31)The role of urokinase plasminogen activator (uPA) in idiopathic pulmonary fibrosis (IPF) remains unclear. uPA-generated plasmin has potent fibrogenic actions involving protease activated receptor-1 (PAR-1) and interleukin-6 ...