Pharmacology and Therapeutics
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(FRONTIERS MEDIA SA, 2018-09-21)Heart failure (HF) is a debilitating and deadly chronic disease, with almost 50% of patients with HF dying within 5 years of diagnosis. With limited effective therapies to treat or cure HF, new therapies are greatly needed. ...
Developmental differences in the regulation and functional capacity of ABC efflux transporters at brain barrier interfaces (2019)The safety and potential risks of many medications used in treating pregnant women and newborn children are not well defined. This is, in part, due to limited knowledge of how readily drugs transfer into integral organs ...
Polymyxins–Curcumin Combination Antimicrobial Therapy: Safety Implications and Efficacy for Infection Treatment (Molecular Diversity Preservation International (MDPI) AG, 2020-06-09)The emergence of antimicrobial resistance in Gram‐negative bacteria poses a huge health challenge. The therapeutic use of polymyxins (i.e., colistin and polymyxin B) is commonplace due to high efficacy and limiting treatment ...