• MYC in Brain Development and Cancer. 

  Zaytseva, O; Kim, N-H; Quinn, LM (MDPI AG, 2020-10-20)

  The MYC family of transcriptional regulators play significant roles in animal development, including the renewal and maintenance of stem cells. Not surprisingly, given MYC's capacity to promote programs of proliferative ...

• Transcriptional Memory-Like Imprints and Enhanced Functional Activity in gamma delta T Cells Following Resolution of Malaria Infection 

  Kumarasingha, R; Ioannidis, LJ; Abeysekera, W; Studniberg, S; Wijesurendra, D; Mazhari, R; Poole, DP; Mueller, I; Schofield, L; Hansen, DS; ... (FRONTIERS MEDIA SA, 2020-10-14)

  γδ T cells play an essential role in the immune response to many pathogens, including Plasmodium. However, long-lasting effects of infection on the γδ T cell population still remain inadequately understood. This study ...

• Pharmacological validation of targets regulating CD14 during macrophage differentiation. 

  Jimenez-Duran, G; Luque-Martin, R; Patel, M; Koppe, E; Bernard, S; Sharp, C; Buchan, N; Rea, C; de Winther, MPJ; Turan, N; ... (Elsevier BV, 2020-11)

  The signalling receptor for LPS, CD14, is a key marker of, and facilitator for, pro-inflammatory macrophage function. Pro-inflammatory macrophage differentiation remains a process facilitating a broad array of disease ...

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