Physiology - Research Publications
Now showing items 1-10 of 72
Stimulation of Angiotensin Type 1A Receptors on Catecholaminergic Cells Contributes to Angiotensin-Dependent Hypertension
(LIPPINCOTT WILLIAMS & WILKINS, 2013-11-01)
Hypertension contributes to multiple forms of cardiovascular disease and thus morbidity and mortality. The mechanisms inducing hypertension remain unclear although the involvement of homeostatic systems, such as the ...
Pregnancy in aged rats that were born small: cardiorenal and metabolic adaptations and second-generation fetal growth
(FEDERATION AMER SOC EXP BIOL, 2012-10-01)
Uteroplacental insufficiency is associated with adult cardiorenal and metabolic diseases, particularly in males. Pregnancy is the greatest physiological challenge facing women, and those born small are at increased risk ...
Properties of cholinergic and non-cholinergic submucosal neurons along the mouse colon
Key pointsSubmucosal neurons are crucial regulators of gut secretion. Despite significant interest in using mouse models for enteric neuropathies, much is still unknown about their submucous innervation.We examined properties ...
Molecular Basis of Impaired Glycogen Metabolism during Ischemic Stroke and Hypoxia
(PUBLIC LIBRARY SCIENCE, 2014)
Background: Ischemic stroke is the combinatorial effect of many pathological processes including the loss of energy supplies, excessive intracellular calcium accumulation, oxidative stress, and inflammatory responses. The ...
Alterations in Notch signalling in skeletal muscles from mdx and dko dystrophic mice and patients with Duchenne muscular dystrophy
(The Physiological Society, 2014)
In Duchenne muscular dystrophy (DMD), muscle damage and impaired regeneration lead to progressive muscle wasting, weakness and premature death. The Notch signalling pathway represents a central regulator of gene expression ...
Dietary protein and exercise training in ageing
(Cambridge University Press, 2010)
Ageing is accompanied by a progressive loss of skeletal muscle mass and strength, leading to the loss of functional capacity and an increased risk for developing chronic metabolic diseases such as diabetes. The age-related ...