Surgery (Austin & Northern Health) - Research Publications
Now showing items 1-10 of 45
Induction of Gastrin Expression in Gastrointestinal Cells by Hypoxia or Cobalt Is Independent of Hypoxia-Inducible Factor (HIF)
(ENDOCRINE SOC, 2012-07-27)
Gastrin and its precursors have been shown to promote mitogenesis and angiogenesis in gastrointestinal tumors. Hypoxia stimulates tumor growth, but its effect on gastrin gene regulation has not been examined in detail. ...
Septic Acute Kidney Injury: The Glomerular Arterioles
Acute kidney injury (AKI) is a serious condition that affects many intensive care unit (ICU) patients. The most common causes of AKI in the ICU are severe sepsis and septic shock. The mortality of AKI in septic critically ...
Relative hyperlactatemia and hospital mortality in critically ill patients: a retrospective multi-centre study
(BIOMED CENTRAL LTD, 2010-01-01)
INTRODUCTION: Higher lactate concentrations within the normal reference range (relative hyperlactatemia) are not considered clinically significant. We tested the hypothesis that relative hyperlactatemia is independently ...
Overview of the study protocols and statistical analysis plan for the Saline versus Plasma-Lyte 148 for Intravenous Fluid Therapy (SPLIT) research program
(AUSTRALASIAN MED PUBL CO LTD, 2015-03-01)
BACKGROUND: 0.9% saline is the most commonly used intravenous (IV) fluid in the world but recent data raise the possibility that, compared with buffered crystalloid fluids such as Plasma-Lyte 148, the administration of ...
High Affinity Binding of Indium and Ruthenium Ions by Gastrins
(PUBLIC LIBRARY SCIENCE, 2015-10-12)
The peptide hormone gastrin binds two ferric ions with high affinity, and iron binding is essential for the biological activity of non-amidated forms of the hormone. Since gastrins act as growth factors in gastrointestinal ...
Analysis of the platypus genome suggests a transposon origin for mammalian imprinting
(BIOMED CENTRAL LTD, 2009-01-01)
BACKGROUND: Genomic imprinting is an epigenetic phenomenon that results in monoallelic gene expression. Many hypotheses have been advanced to explain why genomic imprinting evolved in mammals, but few have examined how it ...
Current ventilation practice during general anaesthesia: a prospective audit in Melbourne, Australia
(BIOMED CENTRAL LTD, 2014-10-01)
BACKGROUND: Recent evidence suggests that the use of low tidal volume ventilation with the application of positive end-expiratory pressure (PEEP) may benefit patients at risk of respiratory complications during general ...
Inpatient HbA1c testing: a prospective observational study.
OBJECTIVE: To use admission inpatient glycated hemoglobin (HbA1c) testing to help investigate the prevalence of unrecognized diabetes, the cumulative prevalence of unrecognized and known diabetes, and the prevalence of ...
Slipped capital femoral epiphysis, fixation by single screw in situ: A kinematic and radiographic study
(ELSEVIER SCI LTD, 2014-05-01)
BACKGROUND: Slipped capital femoral epiphysis is known to produce characteristic deformities in the proximal femur, which affect hip motion and may cause a limp. This paper assessed the 3D gait kinematics in adolescents ...