Surgery (Austin & Northern Health) - Research Publications
Now showing items 1-10 of 69
Induction of Gastrin Expression in Gastrointestinal Cells by Hypoxia or Cobalt Is Independent of Hypoxia-Inducible Factor (HIF)
(ENDOCRINE SOC, 2012-07-27)
Gastrin and its precursors have been shown to promote mitogenesis and angiogenesis in gastrointestinal tumors. Hypoxia stimulates tumor growth, but its effect on gastrin gene regulation has not been examined in detail. ...
Single Port Trans-gastric Reversal of High Gastric Reduction
BACKGROUND: Stomal stenosis is common following high gastric reduction or vertical banded gastroplasty for obesity. Open and laparoscopic approaches for reversal can be problematic due to expected adhesions from previous ...
Multidisciplinary Treatment and Survival of Patients with Vertebral Metastases from Thyroid Carcinoma
(MARY ANN LIEBERT, INC, 2012-02-01)
BACKGROUND: Distant metastases from differentiated thyroid carcinoma occur in up to 20% of cases and represent the most frequent cause of thyroid cancer-related death. Metastatic disease to the spine has the potential to ...
Interval to biochemical recurrence following radical prostatectomy does not affect survival in men with low-risk prostate cancer
OBJECTIVES: To evaluate the temporal relationship between interval to biochemical recurrence (BCR) following radical prostatectomy (RP) and prostate cancer-specific mortality (PCSM). PATIENTS AND METHODS: The study comprised ...
An in vivo mouse model of intraosseous spinal cancer causing evolving paraplegia
The spine is the commonest site of skeletal metastatic disease and uncontrolled growth of cancer in the spine will inevitably cause pain and neurologic compromise. Improved understanding of the pathobiology behind this ...
Defining the Substrate Specificity Determinants Recognized by the Active Site of C-Terminal Src Kinase-Homologous Kinase (CHK) and Identification of beta-Synuclein as a Potential CHK Physiological Substrate
(AMER CHEMICAL SOC, 2011-08-09)
C-Terminal Src kinase-homologous kinase (CHK) exerts its tumor suppressor function by phosphorylating the C-terminal regulatory tyrosine of the Src-family kinases (SFKs). The phosphorylation suppresses their activity and ...
A conceptual model for analysing informal learning in online social networks for health professionals
(IOS PRESS, 2014-01-01)
Online social networking (OSN) provides a new way for health professionals to communicate, collaborate and share ideas with each other for informal learning on a massive scale. It has important implications for ongoing ...
Analysing Health Professionals' Learning Interactions in an Online Social Network: A Longitudinal Study
(IOS PRESS, 2016-01-01)
This paper summarises a longitudinal analysis of learning interactions occurring over three years among health professionals in an online social network. The study employs the techniques of Social Network Analysis (SNA) ...
MEK-ERK signaling diametrically controls the stimulation of IL-23p19 and EBI3 expression in epithelial cells by IL-36
Interleukin (IL)-36 cytokines are important regulators of mucosal homeostasis and inflammation. We previously established that oral epithelial cells strongly upregulate IL-36γ expression in response to the bacterial pathogen ...