Surgery (Austin & Northern Health) - Research Publications

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Induction of Gastrin Expression in Gastrointestinal Cells by Hypoxia or Cobalt Is Independent of Hypoxia-Inducible Factor (HIF)

Xiao, Lin; Kovac, Suzana; Chang, Mike; Shulkes, Arthur; Baldwin, Graham S.; Patel, Oneel (ENDOCRINE SOC, 2012-07-27)

Gastrin and its precursors have been shown to promote mitogenesis and angiogenesis in gastrointestinal tumors. Hypoxia stimulates tumor growth, but its effect on gastrin gene regulation has not been examined in detail. ...

Isolation and characterisation of the ovine gastrin-releasing peptide gene; abundant expression in the pregnant uterus and selective expression in fetal tissues

WHITLEY, JANE; MOORE, CAROLINE; GIRAUD, ANDREW SIMON; SHULKES, ARTHUR AARON (2002)

Single Port Trans-gastric Reversal of High Gastric Reduction

Aly, A; Sweeney, T; Michell, I; Lim, K (SPRINGER, 2014-03-01)

BACKGROUND: Stomal stenosis is common following high gastric reduction or vertical banded gastroplasty for obesity. Open and laparoscopic approaches for reversal can be problematic due to expected adhesions from previous ...

Multidisciplinary Treatment and Survival of Patients with Vertebral Metastases from Thyroid Carcinoma

Quan, GMY; Pointillart, V; Palussiere, J; Bonichon, F (MARY ANN LIEBERT, INC, 2012-02-01)

BACKGROUND: Distant metastases from differentiated thyroid carcinoma occur in up to 20% of cases and represent the most frequent cause of thyroid cancer-related death. Metastatic disease to the spine has the potential to ...

Interval to biochemical recurrence following radical prostatectomy does not affect survival in men with low-risk prostate cancer

Bolton, DM; Ta, A; Bagnato, M; Muller, D; Lawrentschuk, NL; Severi, G; Syme, RR; Giles, GG (SPRINGER, 2014-04-01)

OBJECTIVES: To evaluate the temporal relationship between interval to biochemical recurrence (BCR) following radical prostatectomy (RP) and prostate cancer-specific mortality (PCSM). PATIENTS AND METHODS: The study comprised ...

An in vivo mouse model of intraosseous spinal cancer causing evolving paraplegia

Cossigny, DAF; Mouhtouris, E; Dushyanthen, S; Gonzalvo, A; Quan, GMY (SPRINGER, 2013-11-01)

The spine is the commonest site of skeletal metastatic disease and uncontrolled growth of cancer in the spine will inevitably cause pain and neurologic compromise. Improved understanding of the pathobiology behind this ...

Defining the Substrate Specificity Determinants Recognized by the Active Site of C-Terminal Src Kinase-Homologous Kinase (CHK) and Identification of beta-Synuclein as a Potential CHK Physiological Substrate

Ia, KK; Jeschke, GR; Deng, Y; Kamaruddin, MA; Williamson, NA; Scanlon, DB; Culvenor, JG; Hossain, MI; Purcell, AW; Liu, S; ... (AMER CHEMICAL SOC, 2011-08-09)

C-Terminal Src kinase-homologous kinase (CHK) exerts its tumor suppressor function by phosphorylating the C-terminal regulatory tyrosine of the Src-family kinases (SFKs). The phosphorylation suppresses their activity and ...

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