Medicine (RMH Academic Centre)
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Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A
(OXFORD UNIV PRESS, 2013-10-01)Epilepsy comprises several syndromes, amongst the most common being mesial temporal lobe epilepsy with hippocampal sclerosis. Seizures in mesial temporal lobe epilepsy with hippocampal sclerosis are typically drug-resistant, ... -
Mortality in dialysis patients may not be associated with ESA dose: a 2-year prospective observational study
(BMC, 2012-06-15)BACKGROUND: Anaemia of chronic kidney disease increases the risk of death and adverse events, but can be managed using erythropoiesis stimulating agents (ESAs). However, recent evidence suggests that targeting a higher ... -
Investigating the Potential Role of Genetic and Epigenetic Variation of DNA Methyltransferase Genes in Hyperplastic Polyposis Syndrome
(PUBLIC LIBRARY SCIENCE, 2011-02-10)BACKGROUND: Hyperplastic Polyposis Syndrome (HPS) is a condition associated with multiple serrated polyps, and an increased risk of colorectal cancer (CRC). At least half of CRCs arising in HPS show a CpG island methylator ...