Medicine (RMH) - Research Publications
Now showing items 1-10 of 559
Investigating well-being, work limitations and preferences for self-management education and peer support among younger people with hip and knee osteoarthritis: protocol for a cross-sectional study
(BMJ PUBLISHING GROUP, 2013-12-01)
Introduction: Osteoarthritis (OA) has traditionally been considered a condition of older age. However, younger people are also affected by hip and knee OA, often as a result of sporting and work-related injuries. As OA ...
Left Septal Atrial Tachycardias: Electrocardiographic and Electrophysiologic Characterization of a Paraseptal Focus
Left Septal Atrial Tachycardias.Objective: The objective was to characterize the electrocardiographic and electrophysiological features of focal atrial tachycardia (FAT) originating from the left septum (LS). Background: ...
Anti-EGFR therapeutic efficacy correlates directly with inhibition of STAT3 activity
(LANDES BIOSCIENCE, 2014-05-27)
Several agents targeting the epidermal growth factor receptor (EGFR) have been FDA-approved to treat cancer patients with varying tumor types including metastatic colorectal cancer. Many patients treated with anti-EGFR ...
Insight Into the Pathogenesis of Fetal Growth Restriction in Placental Malaria: Decreased Placental Glucose Transporter Isoform 1 Expression
(OXFORD UNIV PRESS INC, 2014-05-27)
Placental malaria, especially when complicated with intervillositis, can cause fetal growth restriction. Transplacental glucose transport by glucose transporter isoform 1 (GLUT-1) on the syncytiotrophoblast microvillous ...
Ethosuximide reduces epileptogenesis and behavioral comorbidity in the GAERS model of genetic generalized epilepsy
Purpose Ethosuximide (ESX) is a drug of choice for the symptomatic treatment of absence seizures. Chronic treatment with ESX has been reported to have disease-modifying antiepileptogenic activity in the WAG/Rij rat model ...
Peripheral Blood Mononuclear Cells Derived from Grand Multigravidae Display a Distinct Cytokine Profile in Response to P. falciparum Infected Erythrocytes
(PUBLIC LIBRARY SCIENCE, 2014)
Immunopathology of placental malaria is most significant in women in their first pregnancy especially in endemic areas, due to a lack of protective immunity to Plasmodium falciparum, which is acquired in successive ...
Does Malaria Affect Placental Development? Evidence from In Vitro Models
(PUBLIC LIBRARY SCIENCE, 2013)
Background: Malaria in early pregnancy is difficult to study but has recently been associated with fetal growth restriction (FGR). The pathogenic mechanisms underlying malarial FGR are poorly characterized, but may include ...
Access to self-management education, conservative treatment and surgery for arthritis according to socioeconomic status
There is now a considerable body of research investigating inequities in access to health care for arthritis according to socioeconomic status (SES). Conducted in a range of settings internationally, studies have examined ...
Challenges in evaluating an arthritis self-management program for people with hip and knee osteoarthritis in ‘real world’ clinical settings
(Journal of Rheumatology Publishing Company Limited, 2012)
Objective: To evaluate the influence of a 6-week Arthritis Self-Management Program (ASMP) on health-related quality of life (HRQOL) and self-management skills in clinical settings. Methods: Individuals with hip or knee ...