Medicine (RMH) - Theses
Now showing items 1-10 of 141
Falling down the cascade: the gaps in care delivery for people living with chronic hepatitis B in Australia
In Australia, an estimated 239,000 people were living with chronic hepatitis B (CHB) in 2016. Most of the affected community were born overseas and acquired their infection early in life, in countries with high and ...
Pre-clinical applications of endobronchial ultrasound in lung cancer
The last decade has seen a paradigm shift in the clinical approach to lung cancer. Treatment has evolved from empirical to rational, based on molecular profiling of tissue obtained by minimally invasive techniques such as ...
Antiepileptic drug teratogenicity: a human and laboratory translational study
Antiepileptic drug (AED) associated teratogenicity has been well documented in the literature. The risk of physical birth defects during the first trimester of pregnancy is increased threefold for most AEDs and over ten-fold ...
Gamma oscillations in animal models of schizophrenia
Schizophrenia is a complex neuropsychiatric disorder most prominently characterised by psychotic symptoms as well as a multitude of sensory and cognitive disturbances. Recent heuristic models of schizophrenia propose that ...
The neuropsychiatric disorders of focal epilepsy
Neuropsychiatric disorders commonly co-exist with focal epilepsy. Despite intense investigation there remains significant limitations to our current understanding of the aetiological relationship between these conditions, ...
Stroke and atrial fibrillation: better detection, effects on infarct evolution and outcome
Ischemic stroke is the commonest stroke and a leading cause of disability and death worldwide. Atrial fibrillation (AF) is the most frequent persistent cardiac arrhythmia and a preventable cause of ischemic strokes. The ...
Vitamin D status and related health in young women: the Safe-D study
Background: Vitamin D deficiency is emerging as a global public health issue in all age groups and public interest in vitamin D has increased significantly over the past decade. Deficiency is associated with increased risk ...
Social engagement and changing cognitive health in ageing
Dementia and Alzheimer’s disease, taken together, are now one of the leading causes of death and disease in the developed world. This is particularly concerning for older women, who are more likely to develop dementia than ...
Reducing acute respiratory complications in thoracolumbar spinal cord injury
Acute traumatic thoracolumbar spinal cord injury (TLSCI) is a devastating event, generally resulting in severe neurological deficits and often profoundly impacting respiratory function. Whilst relatively rare, each new ...
Insights into the mechanisms and effects of right ventricular septal pacing
Cardiac pacemakers have markedly improved the morbidity and survival of patients with bradyarrhythmias. However, major clinical trials have demonstrated that the traditional pacing site, the right ventricular apex (RVA), ...