In Australia, an estimated 239,000 people were living with chronic hepatitis B (CHB) in 2016. Most of the affected community were born overseas and acquired their infection early in life, in countries with high and ...

The last decade has seen a paradigm shift in the clinical approach to lung cancer. Treatment has evolved from empirical to rational, based on molecular profiling of tissue obtained by minimally invasive techniques such as ...

Antiepileptic drug (AED) associated teratogenicity has been well documented in the literature. The risk of physical birth defects during the first trimester of pregnancy is increased threefold for most AEDs and over ten-fold ...

Schizophrenia is a complex neuropsychiatric disorder most prominently characterised by psychotic symptoms as well as a multitude of sensory and cognitive disturbances. Recent heuristic models of schizophrenia propose that ...

Neuropsychiatric disorders commonly co-exist with focal epilepsy. Despite intense investigation there remains significant limitations to our current understanding of the aetiological relationship between these conditions, ...

Ischemic stroke is the commonest stroke and a leading cause of disability and death worldwide. Atrial fibrillation (AF) is the most frequent persistent cardiac arrhythmia and a preventable cause of ischemic strokes. The ...

Background: Vitamin D deficiency is emerging as a global public health issue in all age groups and public interest in vitamin D has increased significantly over the past decade. Deficiency is associated with increased risk ...

Dementia and Alzheimer’s disease, taken together, are now one of the leading causes of death and disease in the developed world. This is particularly concerning for older women, who are more likely to develop dementia than ...

Acute traumatic thoracolumbar spinal cord injury (TLSCI) is a devastating event, generally resulting in severe neurological deficits and often profoundly impacting respiratory function. Whilst relatively rare, each new ...

Cardiac pacemakers have markedly improved the morbidity and survival of patients with bradyarrhythmias. However, major clinical trials have demonstrated that the traditional pacing site, the right ventricular apex (RVA), ...