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  • Expanded complement of Niemann-Pick type C2-like protein genes in Clonorchis sinensis suggests functions beyond sterol binding and transport 

    Anari, M; Stroehlein, AJ; Hall, RS; Chang, BCH; Gasser, RB; Young, ND (BMC, 2020-01-23)
    BACKGROUND: The parasitic flatworm Clonorchis sinensis inhabits the biliary tree of humans and other piscivorous mammals. This parasite can survive and thrive in the bile duct, despite exposure to bile constituents and ...
  • Adenylosuccinic acid therapy ameliorates murine Duchenne Muscular Dystrophy 

    Timpani, CA; Goodman, CA; Stathis, CG; White, JD; Mamchaoui, K; Butler-Browne, G; Gueven, N; Hayes, A; Rybalka, E (NATURE PUBLISHING GROUP, 2020-01-24)
    Arising from the ablation of the cytoskeletal protein dystrophin, Duchenne Muscular Dystrophy (DMD) is a debilitating and fatal skeletal muscle wasting disease underpinned by metabolic insufficiency. The inability to ...
  • Anti-Helicobacter pylori activity of ethoxzolamide. 

    Modak, JK; Tikhomirova, A; Gorrell, RJ; Rahman, MM; Kotsanas, D; Korman, TM; Garcia-Bustos, J; Kwok, T; Ferrero, RL; Supuran, CT; ... (Taylor & Francis Open, 2019-12-01)
    Ethoxzolamide (EZA), acetazolamide, and methazolamide are clinically used sulphonamide drugs designed to treat non-bacteria-related illnesses (e.g. glaucoma), but they also show antimicrobial activity against the gastric ...

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