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Restrictive versus liberal fluid therapy in major abdominal surgery (RELIEF): rationale and design for a multicentre randomised trial
(BMJ PUBLISHING GROUP, 2017-02-01)INTRODUCTION: The optimal intravenous fluid regimen for patients undergoing major abdominal surgery is unclear. However, results from many small studies suggest a restrictive regimen may lead to better outcomes. A large, ... -
Aedes aegypti has spatially structured and seasonally stable populations in Yogyakarta, Indonesia
(BMC, 2015-12-01)BACKGROUND: Dengue fever, the most prevalent global arboviral disease, represents an important public health problem in Indonesia. Control of dengue relies on the control of its main vector, the mosquito Aedes aegypti, yet ... -
Glucocorticoids promote apoptosis of proinflammatory monocytes by inhibiting ERK activity
(NATURE PUBLISHING GROUP, 2018-02-15)Glucocorticoids (GCs) are potent anti-inflammatory drugs whose mode of action is complex and still debatable. One likely cellular target of GCs are monocytes/macrophages. The role of GCs in monocyte survival is also debated. ...