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Restrictive versus liberal fluid therapy in major abdominal surgery (RELIEF): rationale and design for a multicentre randomised trial

Myles, P; Bellomo, R; Corcoran, T; Forbes, A; Wallace, S; Peyton, P; Christophi, C; Story, D; Leslie, K; Serpell, J; ... (BMJ PUBLISHING GROUP, 2017-02-01)

INTRODUCTION: The optimal intravenous fluid regimen for patients undergoing major abdominal surgery is unclear. However, results from many small studies suggest a restrictive regimen may lead to better outcomes. A large, ...

Aedes aegypti has spatially structured and seasonally stable populations in Yogyakarta, Indonesia

Rasic, G; Endersby-Harshman, N; Tantowijoyo, W; Goundar, A; White, V; Yang, Q; Filipovic, I; Johnson, P; Hoffmann, AA; Arguni, E (BMC, 2015-12-01)

BACKGROUND: Dengue fever, the most prevalent global arboviral disease, represents an important public health problem in Indonesia. Control of dengue relies on the control of its main vector, the mosquito Aedes aegypti, yet ...

Glucocorticoids promote apoptosis of proinflammatory monocytes by inhibiting ERK activity

Achuthan, A; Aslam, ASM; Quyen, N; Lam, P-Y; Fleetwood, AJ; Frye, AT; Louis, C; Lee, M-C; Smith, JE; Cook, AD; ... (NATURE PUBLISHING GROUP, 2018-02-15)

Glucocorticoids (GCs) are potent anti-inflammatory drugs whose mode of action is complex and still debatable. One likely cellular target of GCs are monocytes/macrophages. The role of GCs in monocyte survival is also debated. ...

Global optimisation of chiller sequencing and load balancing using Shuffled Complex Evolution

Stewart, I; Aye, L; Peterson, T (International Building Performance Simulation Association & AIRAH, 2017-11-15)

A new model has been developed to optimise the sequencing and load balancing of chillers in the central plants of commercial buildings with multiple water-cooled chillers. The model uses the Shuffled Complex Evolution ...