Centre for Eye Research Australia (CERA)
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The impact of diabetic retinopathy on quality of life: qualitative findings from an item bank development project (SPRINGER, 2012-12-01)PURPOSE: Assessing the efficacy of treatment modalities for diabetic retinopathy (DR) from the patient's perspective is restricted due to a lack of a comprehensive patient-reported outcome measure. We are developing a ...
Study of mitochondrial respiratory defects on reprogramming to human induced pluripotent stem cells (IMPACT JOURNALS LLC, 2016-05-01)Reprogramming of somatic cells into a pluripotent state is known to be accompanied by extensive restructuring of mitochondria and switch in metabolic requirements. Here we utilized Leber's hereditary optic neuropathy (LHON) ...
Altered biometal homeostasis is associated with CLN6 mRNA loss in mouse neuronal ceroid lipofuscinosis (COMPANY OF BIOLOGISTS LTD, 2013-06-15)Neuronal ceroid lipofuscinoses, the most common fatal childhood neurodegenerative illnesses, share many features with more prevalent neurodegenerative diseases. Neuronal ceroid lipofuscinoses are caused by mutations in CLN ...