Medicine (St Vincent's) - Research Publications

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Brain Remodelling following Endothelin-1 Induced Stroke in Conscious Rats

ABEYSINGHE, HIMA; Bokhari, Laita; Dusting, Gregory J.; Roulston, Carli L. (PUBLIC LIBRARY SCIENCE, 2014-05-01)

The extent of stroke damage in patients affects the range of subsequent pathophysiological responses that influence recovery. Here we investigate the effect of lesion size on development of new blood vessels as well as ...

Performance of formulas for estimating glomerular filtration rate in Indigenous Australians with and without Type 2 diabetes: the eGFR Study

Maple-Brown, L. J.; Ekinci, E. I.; Hughes, J. T.; Chatfield, M.; Lawton, P. D.; Jones, G. R. D.; Ellis, A. G.; Sinha, A.; Cass, A.; Hoy, W. E.; ... (WILEY-BLACKWELL, 2014-07-27)

Aims It has been proposed that the Chronic Kidney Disease Epidemiology Collaboration formula estimates glomerular filtration rate more accurately than the Modification of Diet in Renal Disease formula. With the very high ...

Nutritional impacts of a fruit and vegetable subsidy programme for disadvantaged Australian Aboriginal children

Black, Andrew P.; Vally, Hassan; Morris, Peter; Daniel, Mark; Esterman, Adrian; Karschimkus, Connie S.; O'Dea, Kerin (CAMBRIDGE UNIV PRESS, 2013-12-27)

Healthy food subsidy programmes have not been widely implemented in high-income countries apart from the USA and the UK. There is, however, interest being expressed in the potential of healthy food subsidies to complement ...

Dysregulation of innate immunity in hepatitis C virus genotype 1 IL28B-unfavorable genotype patients: Impaired viral kinetics and therapeutic response

Naggie, Susanna; Osinusi, Anu; Katsounas, Antonios; Lempicki, Richard; Herrmann, Eva; Thompson, Alexander J.; Clark, Paul J.; Patel, Keyur; Muir, Andrew J.; McHutchison, John G.; ... (WILEY-BLACKWELL, 2012-08-27)

Recent studies have shown that a single-nucleotide polymorphism upstream of the interleukin-28B (IL28B) gene plays a major role in predicting therapeutic response in hepatitis C virus (HCV)-infected patients treated with ...

Bacterial and fungal microbiota in relation to probiotic therapy (VSL#3) in pouchitis

Kuhbacher, T.; Ott, S. J.; Helwig, U.; Mimura, T.; Rizzello, F.; Kleesen, B.; Gionchetti, P.; Blaut, M.; Campieri, M.; Folsch, U. R.; ... (2006)

Background: The intestinal microbiota plays a critical role in the pathophysiology of pouchitis, a major complication after ileal pouch anal anastomosis in patients with ulcerative colitis. Recently, controlled trials have ...

Impact of multimorbidity count on all-cause mortality and glycaemic outcomes in people with type 2 diabetes: a systematic review protocol

Chiang, JI; Furler, J; Mair, FS; Jani, B; Nicholl, BI; Jenkins, A; Condron, P; O'Neal, D; Manski-Nankervis, J-A (BMJ PUBLISHING GROUP, 2018-04-01)

INTRODUCTION: Type 2 diabetes (T2D) is a leading health priority worldwide. Multimorbidity (MM) is a term describing the co-occurrence of two or more chronic diseases or conditions. The majority of people living with T2D ...

Natural killer T cell defects in multiple myeloma and the impact of lenalidomide therapy

Chan, AC; Neeson, P; Leeansyah, E; Tainton, K; Quach, H; Prince, HM; Harrison, SJ; Godfrey, DI; Ritchie, D; Berzins, SP (WILEY-BLACKWELL, 2014-01-01)

The causes of multiple myeloma (MM) remain obscure and there are few known risk factors; however, natural killer T (NKT) cell abnormalities have been reported in patients with MM, and therapeutic targeting of NKT cells is ...

Hepatitis B surface antigen quantification: Why and how to use it in 2011-A core group report

Chan, HL-Y; Thompson, A; Martinot-Peignoux, M; Piratvisuth, T; Cornberg, M; Brunetto, MR; Tillmann, HL; Kao, J-H; Jia, J-D; Wedemeyer, H; ... (ELSEVIER SCIENCE BV, 2011-11-01)

Quantitative HBsAg had been suggested to be helpful in management of HBV, but assays were cumbersome. The recent availability of commercial quantitative assays has restarted the interest in quantitative serum hepatitis B ...

Electrical receptive fields of retinal ganglion cells: Influence of presynaptic neurons

Maturana, MI; Apollo, NV; Garrett, DJ; Kameneva, T; Cloherty, SL; Grayden, DB; Burkitt, AN; Ibbotson, MR; Meffin, H (PUBLIC LIBRARY SCIENCE, 2018-02-01)

Implantable retinal stimulators activate surviving neurons to restore a sense of vision in people who have lost their photoreceptors through degenerative diseases. Complex spatial and temporal interactions occur in the ...

An evaluation of the telehealth facilitation of diabetes and cardiovascular care in remote Australian Indigenous communities: - protocol for the telehealth eye and associated medical services network [TEAMSnet] project, a pre-post study design

Brazionis, L; Jenkins, A; Keech, A; Ryan, C; Bursell, S-E (BIOMED CENTRAL LTD, 2017-01-05)

BACKGROUND: Despite substantial investment in detection, early intervention and evidence-based treatments, current management strategies for diabetes-associated retinopathy and cardiovascular disease are largely based on ...

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