Active treatment options for patients with metastatic colorectal cancer (CRC) have evolved significantly over the last 20 years. During this time, the median overall survival of these patients has approximately doubled. ...

HFE haemochromatosis is the most common iron overload disease. Since the discovery of the HFE gene is 1996, it is readily diagnosed using a genetic test rather than using liver biopsies. It is an autosomal recessive disease ...

A state of genetic chimerism is created by allogenic transplantation, the quality and quantity of which may have diagnostic significance. The monitoring of cellular macrochimerism following allogeneic hematopoietic cell ...

Obesity in women of child-bearing age is common. There is little evidence that modest weight loss using lifestyle modification alters pregnancy outcomes. Bariatric surgery results in substantial weight loss, which reduces ...

Non-alcoholic fatty liver disease (NAFLD) is the most prevalent liver disease in Australia and around the world and affects up to 40% of the adult population. It is the leading cause for liver transplantation in the USA ...

Gene expression experiments are conducted to better understand the biological mechanisms in cells and tissues. Examples of the wide range of research and clinical applications of gene expression analysis include: identifying ...

The interstitial lung diseases (ILD) are a diverse group of inflammatory and fibrotic lung conditions which cause significant morbidity and mortality. The prototypic ILD, idiopathic pulmonary fibrosis, is the most common ...

Portal hypertension (PHT) and bleeding from gastroesophageal varices is the major cause of morbidity and mortality in cirrhotic patients. In cirrhotics, splanchnic vasodilatation leading to an elevated portal venous inflow ...

Cytomegalovirus (CMV) infects the majority of the world’s population and establishes a life-long infection, which requires intact T cell responses to control. Infants in utero and immune-compromised populations are most ...

Aim To investigate the effects of warmed, humidified CO2 on peritoneal inflammation and tissue damage, tumor microenvironment, and perioperative outcomes in colorectal cancer surgery. Methods • A literature review ...