Background: Systematic reviews demonstrate that Advance Care Planning has many positive effects for residents of residential aged care facilities, including decreased hospitalisation. The proposed residential aged care ...

Psychiatry has lagged behind other fields within the cognitive sciences regarding the analysis of dimensional constructs. This has surely improved recently by diagnostic classifications’ organisation of communication around ...

The impact of antibiotic allergy and its implications for antimicrobial stewardship (AMS) in Australia has been previously ill defined. Whilst removal of patient-reported antibiotic allergy (so-called antibiotic allergy ...

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide and results in significant morbidity and mortality when it progresses to steatohepatitis and liver cancer. Advanced glycation end-products ...

Malignant pleural mesothelioma (MPM) is a rare but deadly malignancy. Despite predictions, worldwide incidences have not significantly diminished and available therapeutic modalities have failed to improve outcomes. There ...

The local renin angiotensin system (RAS) plays a central role in hepatic fibrogenesis. The protective (alternate), angiotensin converting enzyme 2 (ACE2) dependent arm of the RAS and its effector peptide, angiotensin-(1-7), ...

Colorectal cancer is characterized by aberrant cell proliferation, resistance to apoptosis and loss of differentiation. While the pathways which drive cell proliferation and resistance to apoptosis in this disease are ...

Context: Whilst testosterone treatment is indicated for men with classical hypogonadism, there is no consensus as to whether treatment should be given to men with functional hypogonadism due to paucity of high-quality ...

Chronic inflammatory diseases are a global health concern, with 36 million deaths worldwide in 2008 being attributed to chronic inflammatory diseases (Lozano et al. 2012). These chronic inflammatory diseases can be ...

Selenoprotein S (Seps1) is a transmembrane protein that was initially discovered in the diabetic animal model, Psammonys obesus (P. obesus) where its hepatic gene expression was found to be increased by fasting. Subsequently, ...