Biochemistry and Pharmacology
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(2021)Most biological processes are intrinsically coordinated through complex networks of protein-protein interactions. The diversity and the scale of these networks of interactions offer a highly selective and tunable way of ...
Genetic Variants in ERAP1 and ERAP2 Associated With Immune-Mediated Diseases Influence Protein Expression and the Isoform Profile (WILEY, 2018-02-01)OBJECTIVE: Endoplasmic reticulum aminopeptidase 1 (ERAP-1) and ERAP-2, encoded on chromosome 5q15, trim endogenous peptides for HLA-mediated presentation to the immune system. Polymorphisms in ERAP1 and/or ERAP2 are strongly ...
(WILEY, 2018-01-15)KEY POINTS: Cardiac hypertrophy following endurance-training is thought to be due to hypertrophy of existing cardiomyocytes. The benefits of endurance exercise on cardiac hypertrophy are generally thought to be short-lived ...