Melbourne Medical School Collected Works - Research Publications
Now showing items 1-10 of 257
[Review of the book Facing death: a companion in words and images]
(Cambridge University Press, 2010)
May I have your consent?: informed consent in clinical trials - feasibility in emergency situations
(Cambridge University Press, 2011)
Clinical researchers in acute emergency settings are commonly faced with the difficulty of satisfying the conventional ethical requirement of obtaining informed consent, whilst ensuring a representative group of patients ...
Adolescent resilience: a concept analysis
(ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, 2003-02-01)
There is need for greater clarity around the concept of resilience as it relates to the period of adolescence. Literature on resilience published between 1990 and 2000 and relevant to adolescents aged between 12- and ...
The Role of Liver Fructose-1,6-Bisphosphatase in Regulating Appetite and Adiposity
(AMER DIABETES ASSOC, 2012-05-01)
Liver fructose-1,6-bisphosphatase (FBPase) is a regulatory enzyme in gluconeogenesis that is elevated by obesity and dietary fat intake. Whether FBPase functions only to regulate glucose or has other metabolic consequences ...
Ubiquitous expression of the Pik3ca(H1047R) mutation promotes hypoglycemia, hypoinsulinemia, and organomegaly
(FEDERATION AMER SOC EXP BIOL, 2015-04-01)
Mutations in PIK3CA, the gene encoding the p110α catalytic subunit of PI3K, are among the most common mutations found in human cancer and have also recently been implicated in a range of overgrowth syndromes in humans. We ...
Nicotine dependence in a prospective population-based study of adolescents: the protective role of a functional tyrosine hydroxylase polymorphism
(LIPPINCOTT WILLIAMS & WILKINS, 2004-02-01)
Dopamine is a key neurotransmitter of the mesolimbic reward pathway in the human brain, and tyrosine hydroxylase (TH) is the rate-limiting enzyme in dopamine biosynthesis. Consequently, the gene encoding TH is a strong ...
Genetics and public health - evolution, or revolution?
(B M J PUBLISHING GROUP, 2004-11-01)
During the 19th and early 20th century, public health and genetics shared common ground through similar approaches to health promotion in the population. By the mid-20th century there was a division between public health ...