Surgery (RMH) - Research Publications
Now showing items 1-10 of 52
Oncogenic H-Ras Reprograms Madin-Darby Canine Kidney (MDCK) Cell-derived Exosomal Proteins Following Epithelial-Mesenchymal Transition
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2013-08-27)
Epithelial-mesenchymal transition (EMT) is a highly conserved morphogenic process defined by the loss of epithelial characteristics and the acquisition of a mesenchymal phenotype. EMT is associated with increased aggressiveness, ...
Self-directed simulator echocardiography training: a scalable solution
(AUSTRALIAN SOC ANAESTHETISTS, 2015-05-01)
Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination
(NATURE PUBLISHING GROUP, 2016-03-01)
Chronic stress induces signalling from the sympathetic nervous system (SNS) and drives cancer progression, although the pathways of tumour cell dissemination are unclear. Here we show that chronic stress restructures ...
Memory Impairment in Rats after Desflurane Anesthesia is Age and Dose Dependent
(IOS PRESS, 2015-01-01)
Post-operative cognitive dysfunction (POCD) predominantly affects the elderly who suffer memory and concentration deficits after anesthesia and surgery. Animal studies have demonstrated anesthetic alone may contribute to ...
Benefits and risks of epidural analgesia in cardiac surgery
(OXFORD UNIV PRESS, 2015-07-01)
BACKGROUND: Epidurals provide excellent analgesia for cardiac surgery and may reduce complications. However, their use has been tempered because of concern of the rare, but serious complication of epidural haematoma. The ...
Design and validation of the Regional Anaesthesia Procedural Skills Assessment Tool
The aim of this study was to create and evaluate the validity, reliability and feasibility of the Regional Anaesthesia Procedural Skills tool, designed for the assessment of all peripheral and neuraxial blocks using all ...
Lyn-deficient mice develop severe, persistent asthma: Lyn is a critical negative regulator of Th2 immunity
(AMER ASSOC IMMUNOLOGISTS, 2005-08-01)
The etiology of asthma, a chronic inflammatory disorder of the airways, remains obscure, although T cells appear to be central disease mediators. Lyn tyrosine kinase has been implicated as both a facilitator and inhibitor ...
A critical role of Oct4A in mediating metastasis and disease-free survival in a mouse model of ovarian cancer
(BIOMED CENTRAL LTD, 2015-08-11)
BACKGROUND: High grade epithelial ovarian cancer (EOC) is commonly characterised by widespread peritoneal dissemination and ascites. Metastatic EOC tumour cells can attach directly to neighbouring organs or alternatively, ...