Colorectal cancer (CRC) is a common and life-threatening disease which contributes a significant burden on global health systems. Clinical colorectal cancer registries (CCCRs) are potentially powerful tools in the study ...

Glioblastoma multiforme (GBM) is a heterogeneous and malignant brain tumour with poor survival. Despite current best therapies most patients die within 15 months of diagnosis. These aggressive tumours are thought to recur ...

Background A more detailed understanding of the anatomy of the cutaneous lymphatic system is required in order to preserve its function during various procedures and to reconstruct it following its disruption. There is ...

Much remains to be elucidated regarding the molecular mechanisms driving urothelial carcinoma of the bladder (CaB). While comprehensive molecular analyses of several other cancers such as melanoma and breast cancer have ...

Alveolar macrophages of the lung parenchyma facilitate organ homeostasis and host defence, yet are increased and activated in the lungs of patients with acute and chronic lung conditions. This paradox is attributed to the ...

The lymphatic vasculature is vital for tissue fluid homeostasis. It also enables effective immune surveillance, and aids the transport and absorption of fatty acids. Damaged or faulty lymphatic vessels can lead to an ...

Tumor invasion and metastasis are the major causes of treatment failure in cancer patients and principal contributing factors to cancer morbidity and mortality. However, little is understood about either event at the ...