The majority of cancer fatality is caused by tumor metastasis which is underlined by Epithelial-Mesenchymal-Transition (EMT) and its opposing process Mesenchymal-Epithelial-Transition (MET) at the cellular level. Transforming ...

Background Prostate cancer is a prevalent disease that causes significant morbidity and mortality. Although radical prostatectomy offers excellent disease control, it is associated with significant side effects in some ...

Colorectal cancer is the 4th most common cancer globally and the 2nd most common cancer in Australia. Constitutive activation of Signal Transducer and Activator of Transcription 3 (STAT3) has been observed in over 50% of ...

Background and aims: FDG-avid thyroid incidentalomas (TI) are common findings (2.5%) in patients imaged for staging or treatment response and represent thyroid cancer in approximately 35% of cases. Consequently, the 2015 ...

Colorectal cancer (CRC) is a common and life-threatening disease which contributes a significant burden on global health systems. Clinical colorectal cancer registries (CCCRs) are potentially powerful tools in the study ...

Australia has one of the highest cancer incidences in the world, and while brain cancer is a relatively rare diagnosis, its impact on the Australian healthcare system is significant. Despite being responsible for only 1.4% ...

Secondary lymphoedema is a physically and psychologically debilitating disease caused by inadequate drainage of interstitial tissue fluid, distal to sites of damage to lymphatic vessels. It may develop after any cancer ...

he complex immune system has evolved to defend against pathogens while maintaining self-tolerance. Transforming growth factor-β (TGF-β) is a cytokine employed by many immune cells to suppress autoimmunity and inflammation. ...

Glioblastoma multiforme (GBM) is a heterogeneous and malignant brain tumour with poor survival. Despite current best therapies most patients die within 15 months of diagnosis. These aggressive tumours are thought to recur ...

Background A more detailed understanding of the anatomy of the cutaneous lymphatic system is required in order to preserve its function during various procedures and to reconstruct it following its disruption. There is ...