Microbiology & Immunology
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Homology blocks of Plasmodium falciparum var genes and clinically distinct forms of severe malaria in a local population (BIOMED CENTRAL LTD, 2013-11-06)Background The primary target of the human immune response to the malaria parasite Plasmodium falciparum, P. falciparum erythrocyte membrane protein 1 (PfEMP1), is encoded by the members of the hyper-diverse var gene family. ...
(BMC, 2004-10-01)BACKGROUND: Public health strategies are needed to curb antimalarial drug resistance. Theoretical argument points to an association between malaria transmission and drug resistance although field evidence remains limited. ...
(PUBLIC LIBRARY SCIENCE, 2009-04-17)BACKGROUND: Malaria triggers a high inflammatory response in the host that mediates most of the associated pathologies and contributes to death. The identification of pro-inflammatory molecules derived from Plasmodium is ...