Microbiology & Immunology
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Variation in killer cell immunoglobulin-like receptors and their human leukocyte antigen class I-encoded ligands impacts natural killer cell education and the control of viral infection (2018)The interaction of HLA class I (HLA-I) proteins with inhibitory receptors such as those of the Killer cell Immunoglobulin-like Receptor (KIR) family play a key role in effector function acquisition and target cell ...
(2018)Human immunodeficiency virus (HIV) infection remains a major global health issue. Antiretroviral drugs improve life expectancy and significantly reduce the rate of viral transmission; however, we are far from finding a ...
(2018)HIV-1 establishes a highly stable latent reservoir early in infection, necessitating lifelong combinational antiretroviral therapy. Elimination of the latent reservoir remains a significant roadblock for a functional HIV-1 ...