Otolaryngology - Research Publications
Now showing items 1-10 of 48
Gentamicin administration on the stapes footplate causes greater hearing loss and vestibulotoxicity than round window administration in guinea pigs
Clinically, gentamicin has been used extensively to treat the debilitating symptoms of Meniere's disease and is well known for its vestibulotoxic properties. Until recently, it was widely accepted that the round window ...
Promoting neurite outgrowth from spiral ganglion neuron explants using polypyrrole
(Wiley Periodicals Inc, 2009)
Fast inhibition alters first spike timing in auditory brainstem neurons
(The American Physiological Society, 2004)
Research directions for future generations of cochlear implants
(Whurr Publishers Ltd, 2004)
Physiological and psychophysical research indicates that improved hearing in noise and music appreciation are likely with cochlear implants, with better reproduction of the fine temporospatial patterns of neural response ...
(American Association for the Advancement of Science (AAAS), 2009)
Electrode materials that facilitate interaction with living cells are crucial for the development of next-generation bionic devices.
The prone sleeping position impairs arousability in term infants
OBJECTIVE: To investigate whether the prone sleeping position impaired arousal from sleep in healthy infants and whether this impairment was related to cardiorespiratory variables, temperature, or age. STUDY DESIGN: Healthy ...
Enriched retinal ganglion cells derived from human embryonic stem cells
(NATURE PUBLISHING GROUP, 2016-08-10)
Optic neuropathies are characterised by a loss of retinal ganglion cells (RGCs) that lead to vision impairment. Development of cell therapy requires a better understanding of the signals that direct stem cells into RGCs. ...
Virtual Electrodes by Current Steering in Retinal Prostheses
(ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014-12-01)
PURPOSE: Retinal prostheses are an approved treatment for vision restoration in retinal degenerative diseases; however, present implants have limited resolution and simply increasing the number of electrodes is limited by ...
Drug delivery to the inner ear
(IOP PUBLISHING LTD, 2012-12-01)
Bionic devices electrically activate neural populations to partially restore lost function. Of fundamental importance is the functional integrity of the targeted neurons. However, in many conditions the ongoing pathology ...