Microencapsulation and Characterization of Natural Polyphenols from PHF Extract
AuthorHussain, SA; Hameed, A; Nazir, Y; Naz, T; Wu, Y; Suleria, HAR; Song, Y
University of Melbourne Author/sSuleria, Hafiz Ansar Rasul
AffiliationVeterinary and Agricultural Sciences
Agriculture and Food Systems
Document TypeJournal Article
CitationsHussain, S. A., Hameed, A., Nazir, Y., Naz, T., Wu, Y., Suleria, H. A. R. & Song, Y. Microencapsulation and Characterization of Natural Polyphenols from PHF Extract. https://doi.org/10.20944/preprints201805.0318.v1.
Access StatusAccess this item via the Open Access location
Open Access URLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073146/
<jats:p>Microencapsulation of polyherbal formulation (PHF) extract was carried out by freeze drying method, by employing gum arabic (GA), gelatin (GE), and maltodextrin (MD) with their designated different combinations as encapsulating wall materials. Antioxidant components (i.e total phenolic contents (TPC),Total flavonoids contents (TFC), and total condensed contents (TCT)), antioxidant activity (i.e. DPPH, &beta;-carotene &amp; ABTS+ assays), moisture contents, water activity (aw), solubility, hygroscopicity, glass transition temperature (Tg), particle size, morphology, in vitro alpha-amylase and alpha-glucosidase inhibition and bioavailability ratios of the powders were investigated. Amongst all encapsulated products, TB (5% GA and 5% MD) and TC (10% GA) has proven to be the best treatments with respect to the highest preservation of antioxidant components and their antioxidant potential by DPPH and &beta;-carotene assays and noteworthy for an ABTS+ assays, in addition, the aforesaid treatments also demonstrated lower moisture content, aw, particle size and higher solubility, hygroscopicity and glass transition temperature (Tg). All freeze dried samples showed irregular (asymmetrical) microcrystalline structures. Furthermore, TB and TC also illustrated the highest in vitro anti-diabetic potential due to great potency for inhibiting alpha-amylase and alpha-glucosidase activities. In the perspective of bioavailability, TA, TB and TC demonstrated the excellent bioavailability ratios (%).Futhermore, the phytochemo-profiling of ethanolic extract of PHF was also revealed to find out the bioactive compounds.</jats:p>
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