Otolaryngology - Theses
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Vestibular migraine: a challenging illness to live with and to manage: a qualitative study of patients’ and specialists’ perspectives
Vestibular migraine (VM) is one of the most common causes of recurrent vertigo with significant effects on patients’ health-related quality of life measures and psychological well-being. It is widely accepted that VM is ...
Trauma and residual hearing loss after cochlear implantation surgery
For the last 30 years, cochlear implantation (CI) surgery has been successfully used for the treatment of severe to profound deafness. With improvements in cochlear implant technology, the surgical criteria have expanded ...
A study of electrical stimulation levels over 10 years for adults using Nucleus cochlear implants
Cochlear implants have improved sound perception for thousands of people with severe and profound sensorineural hearing loss. To ensure a good quality sound signal, the implant must be individually programmed throughout ...
Virtual reality for the training of ear surgery
In current residency surgical training programs, residents learn by observing their mentor and practicing under his/her supervision. For patient safety, the mentor needs to ensure that residents have sufficient practice ...
Local delivery of Dexamethasone for the preservation of residual hearing in an animal cochlear implant model
This thesis uses an experimental model of cochlear implantation to examine the hearing protection afforded by the application of dexamethasone to the round window prior to surgery.
A novel vestibulo-cerebellar ataxia, Cerebellar Ataxia with Neuropathy and Vestibular Areflexia Syndrome (CANVAS): clinical phenotype, pathology, imaging, differential diagnoses and a quantitative bedside test
Patients with combined cerebellar and vestibular impairment were first identified in about 1979 and were studied as a pathophysiological model. The syndrome of Cerebellar Ataxia with Bilateral Vestibulopathy (CABV) and ...
Evaluation of the probiotic Streptococcus salivarius fro the inhibition of the pneumococcal colonisation and prevention of otitis media
Otitis media (OM) is one of the commonest infections of infants and young children, being second only to the common cold. Acute OM (AOM) is also the commonest illness of children for which medical attention is sought in ...
The potential of induced pluripotent stem cells for spiral ganglion neuron replacement
In mammals, overexposure to loud noise, ototoxic medication or even ageing can incur irreversible damage to the sensory hair cells and spiral ganglion neurons (SGNs) resulting in sensorineural hearing loss (SNHL). Currently, ...
Signal segregation in bilateral cochlear implant users
Cochlear implant (CI) users can often achieve high levels of speech comprehension in quiet condition but typically face challenges in noisy environments. Under such conditions, the ability to detect, perceive and comprehend ...
Causes of delayed low frequency hearing loss following cochlear implantation
Since the development of the cochlear implant, hearing rehabilitation has been possible for patients with severe to profound hearing loss. The audiological criteria for cochlear implantation is expanding to include more ...