Medical Biology: Recent submissions
Now showing items 1-3 of 333
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Defining programs of cell death that can be harnessed to impact on outcomes of chronic viral infection
(2019)Pathogens causing chronic infections have successfully evolved mechanisms to subvert host immunity. Excessive and inappropriate inflammation together with attrition of repeatedly overstimulated high affinity T cells leads ... -
Insights into mechanisms of resistance to apoptosis in Epstein-Barr virus-associated T and NK cell lymphomas
(2018)Ectopic Epstein-Barr virus (EBV) infection of T or NK cells is associated with several aggressive diseases including extra-nodal NK/T cell lymphoma (ENKTL) and chronic active EBV (CAEBV). Resistance to standard chemotherapy ... -
Investigating circulating miRNA markers of response to triple DMARD therapy, and profiling synovial fluid extracellular vesicles in patients with rheumatoid arthritis
(2019)Rheumatoid arthritis (RA) is a chronic autoimmune disease that occurs due to an abnormal immune response which perpetuates inflammation in affected joints and can lead to the irreversible destruction of articular cartilage ...