Medical Biology: Recent submissions
Now showing items 1-3 of 360
-
Investigating the molecular basis of human NLRP1 inflammasome activation
(2019)Cytosolic sensor proteins like NLRP1 (NOD-like receptor containing a pyrin domain 1) play a fundamental role in mediating innate immunity. Upon activation they form signalling hubs that recruit the adaptor protein ASC ... -
Identify new regulators of TNFR1-induced necroptotic pathway
(2019)Acute Myeloid Leukaemia (AML) is a vastly heterogeneous blood disorder with a poor prognosis for patients older than 65. Our group has been focused on developing new treatments for AML to replace the standard intensive ... -
Identifying Plasmodium vivax encoded proteins that may prevent host cell death during liver development
(2019)Malaria is a major global health problem and a leading cause of death worldwide. The mechanism behind some parts of the parasite life cycle are still obscure, especially the liver stage which is essential for parasite ...