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dc.contributor.authorLi, S
dc.contributor.authorChin, C
dc.contributor.authorThondapu, V
dc.contributor.authorPoon, EKW
dc.contributor.authorMonty, JP
dc.contributor.authorLi, Y
dc.contributor.authorOoi, ASH
dc.contributor.authorTu, S
dc.contributor.authorBarlis, P
dc.date.accessioned2020-05-21T09:06:18Z
dc.date.available2020-05-21T09:06:18Z
dc.date.issued2017-07-01
dc.identifierpii: 10.1007/s10554-017-1093-3
dc.identifier.citationLi, S., Chin, C., Thondapu, V., Poon, E. K. W., Monty, J. P., Li, Y., Ooi, A. S. H., Tu, S. & Barlis, P. (2017). Numerical and experimental investigations of the flow-pressure relation in multiple sequential stenoses coronary artery. INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING, 33 (7), pp.1083-1088. https://doi.org/10.1007/s10554-017-1093-3.
dc.identifier.issn1569-5794
dc.identifier.urihttp://hdl.handle.net/11343/239174
dc.description.abstractVirtual fractional flow reserve (vFFR) has been evaluated as an adjunct to invasive fractional flow reserve (FFR) in the light of its operational and economic benefits. The accuracy of vFFR and the complexity of hyperemic flow simulation are still not clearly understood. This study investigates the flow-pressure relation in an idealised multiple sequential stenoses coronary artery model via numerical and experimental approaches. Pressure drop is linearly correlated with flow rate irrespective of the number of stenosis. Computational fluid dynamics results are in good agreement with the experimental data, demonstrating reasonable accuracy of vFFR. It was also found that the difference between data obtained with steady and pulsatile flows is negligible, indicating the steady flow may be used instead of pulsatile flow conditions in vFFR computation. This study adds to the current understanding of vFFR and may improve its clinical applicability as an adjunct to invasively determined FFR.
dc.languageEnglish
dc.publisherSPRINGER
dc.titleNumerical and experimental investigations of the flow-pressure relation in multiple sequential stenoses coronary artery
dc.typeJournal Article
dc.identifier.doi10.1007/s10554-017-1093-3
melbourne.affiliation.departmentMedicine and Radiology
melbourne.affiliation.departmentMedicine, Northern Health
melbourne.affiliation.departmentMechanical Engineering
melbourne.source.titleINTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
melbourne.source.volume33
melbourne.source.issue7
melbourne.source.pages1083-1088
dc.rights.licenseCC BY
melbourne.elementsid1190684
melbourne.openaccess.pmchttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489574
melbourne.contributor.authorBarlis, Peter
melbourne.contributor.authorPoon, Kingwai
melbourne.contributor.authorMonty, Jason
melbourne.contributor.authorOoi, Andrew
melbourne.contributor.authorLI, SHU
dc.identifier.eissn1573-0743
melbourne.conference.locationUnited States
melbourne.accessrightsOpen Access


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