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    Risk factors for the progression of finger interphalangeal joint osteoarthritis: a systematic review

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    Author
    Shah, K; Yang, X; Lane, JCE; Collins, GS; Arden, NK; Furniss, D; Filbay, SR
    Date
    2020-08-24
    Source Title
    Rheumatology International: clinical and experimental investigations
    Publisher
    SPRINGER HEIDELBERG
    University of Melbourne Author/s
    Filbay, Stephanie
    Affiliation
    Physiotherapy
    Metadata
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    Document Type
    Journal Article
    Citations
    Shah, K., Yang, X., Lane, J. C. E., Collins, G. S., Arden, N. K., Furniss, D. & Filbay, S. R. (2020). Risk factors for the progression of finger interphalangeal joint osteoarthritis: a systematic review. RHEUMATOLOGY INTERNATIONAL, 40 (11), pp.1781-1792. https://doi.org/10.1007/s00296-020-04687-1.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/251549
    DOI
    10.1007/s00296-020-04687-1
    Abstract
    Progressive hand interphalangeal joint (IPJ) osteoarthritis is associated with pain, reduced function and impaired quality of life. However, the evidence surrounding risk factors for IPJ osteoarthritis progression is unclear. Identifying risk factors for IPJ osteoarthritis progression may inform preventative strategies and early interventions to improve long-term outcomes for individuals at risk of IPJ osteoarthritis progression. The objectives of the study were to describe methods used to measure the progression of IPJ osteoarthritis and identify risk factors for IPJ osteoarthritis progression. MEDLINE, EMBASE, Scopus, and The Cochrane Library were searched from inception to 19th February 2020 (PROSPERO CRD42019121034). Eligible studies assessed potential risk factor/s associated with IPJ osteoarthritis progression. Risk of bias was assessed using a modified QUIPS Tool, and a best evidence synthesis was performed. Of eight eligible studies, all measured osteoarthritis progression radiographically, and none considered symptoms. Eighteen potential risk factors were assessed. Diabetes (adjusted mean difference between 2.06 and 7.78), and larger finger epiphyseal index in males (regression coefficient β = 0.202) and females (β = 0.325) were identified as risk factors (limited evidence). Older age in men and women showed mixed results; 13 variables were not risk factors (all limited evidence). Patients with diabetes and larger finger epiphyseal index might be at higher risk of radiographic IPJ osteoarthritis progression, though evidence is limited and studies are biased. Studies assessing symptomatic IPJ osteoarthritis progression are lacking.

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