University Library
  • Login
A gateway to Melbourne's research publications
Minerva Access is the University's Institutional Repository. It aims to collect, preserve, and showcase the intellectual output of staff and students of the University of Melbourne for a global audience.
View Item 
  • Minerva Access
  • Veterinary and Agricultural Sciences
  • Veterinary and Agricultural Sciences Collected Works
  • Veterinary and Agricultural Sciences Collected Works - Research Publications
  • View Item
  • Minerva Access
  • Veterinary and Agricultural Sciences
  • Veterinary and Agricultural Sciences Collected Works
  • Veterinary and Agricultural Sciences Collected Works - Research Publications
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

    Impact of a 3-year mass drug administration pilot project for taeniasis control in Madagascar

    Thumbnail
    Download
    published version (774.5Kb)

    Citations
    Altmetric
    Author
    Ramiandrasoa, NS; Ravoniarimbinina, P; Solofoniaina, AR; Rakotomanga, IPA; Andrianarisoa, SH; Molia, S; Labouche, A-M; Fahrion, AS; Donadeu, M; Abela-Ridder, B; ...
    Date
    2020-09-01
    Source Title
    PLoS Neglected Tropical Diseases
    Publisher
    PUBLIC LIBRARY SCIENCE
    University of Melbourne Author/s
    Donadeu, Meritxell
    Affiliation
    Veterinary and Agricultural Sciences
    Metadata
    Show full item record
    Document Type
    Journal Article
    Citations
    Ramiandrasoa, N. S., Ravoniarimbinina, P., Solofoniaina, A. R., Rakotomanga, I. P. A., Andrianarisoa, S. H., Molia, S., Labouche, A. -M., Fahrion, A. S., Donadeu, M., Abela-Ridder, B. & Rajaonatahina, D. (2020). Impact of a 3-year mass drug administration pilot project for taeniasis control in Madagascar. PLOS NEGLECTED TROPICAL DISEASES, 14 (9), https://doi.org/10.1371/journal.pntd.0008653.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/251597
    DOI
    10.1371/journal.pntd.0008653
    Abstract
    Taenia solium is endemic in Madagascar and presents a significant burden on the population and the health system. The parasite cycles through humans who host the adult tapeworm, and pigs that host the larval stages. Accidental infection of humans may occur with the larval stages which encyst in the nervous central system causing neurocysticercosis, a major cause of seizure disorders and a public health problem. One of the interventions to facilitate the control of the disease is mass drug administration (MDA) of the human population with taeniacide. Here we describe a pilot project conducted in Antanifotsy district of Madagascar from 2015 to 2017 where three annual rounds of MDA (praziquantel, 10mg/Kg) were undertaken in 52 villages. Changes in the prevalence of taeniasis were assessed before, during and after the treatments. A total of 221,308 treatments were given to all eligible people above 5 years of age representing a 95% coverage of the targeted population. No major adverse effects were notified related to the implementation of the MDA. The prevalence of taeniasis was measured using Kato-Katz and copro-antigen techniques. Analyses undertaken combining the results of the Kato-Katz with copro-antigen, or using the Kato-Katz results alone, showed that there was a significant reduction in taeniasis 4 months after the last MDA, but 12 months later (16 months after the last MDA) the taeniasis prevalence had returned to its original levels. Results of the pilot project emphasize the need of a multi-sectorial One-Health approach for the sustained control of T. solium.

    Export Reference in RIS Format     

    Endnote

    • Click on "Export Reference in RIS Format" and choose "open with... Endnote".

    Refworks

    • Click on "Export Reference in RIS Format". Login to Refworks, go to References => Import References


    Collections
    • Minerva Elements Records [52443]
    • Veterinary and Agricultural Sciences Collected Works - Research Publications [329]
    Minerva AccessDepositing Your Work (for University of Melbourne Staff and Students)NewsFAQs

    BrowseCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects
    My AccountLoginRegister
    StatisticsMost Popular ItemsStatistics by CountryMost Popular Authors