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dc.contributor.authorCraig, JM
dc.contributor.authorCalais-Ferreira, L
dc.contributor.authorUmstad, MP
dc.contributor.authorBuchwald, D
dc.date.accessioned2020-11-26T22:46:33Z
dc.date.available2020-11-26T22:46:33Z
dc.date.issued2020-02-01
dc.identifierpii: S1832427420000043
dc.identifier.citationCraig, J. M., Calais-Ferreira, L., Umstad, M. P. & Buchwald, D. (2020). The Value of Twins for Health and Medical Research: A Third of a Century of Progress. TWIN RESEARCH AND HUMAN GENETICS, 23 (1), pp.8-15. https://doi.org/10.1017/thg.2020.4.
dc.identifier.issn1832-4274
dc.identifier.urihttp://hdl.handle.net/11343/251986
dc.description.abstractIn 1984, Hrubec and Robinette published what was arguably the first review of the role of twins in medical research. The authors acknowledged a growing distinction between two categories of twin studies: those aimed at assessing genetic contributions to disease and those aimed at assessing environmental contributions while controlling for genetic variation. They concluded with a brief section on recently founded twin registries that had begun to provide unprecedented access to twins for medical research. Here we offer an overview of the twin research that, in our estimation, best represents the field has progress since 1984. We start by summarizing what we know about twinning. We then focus on the value of twin study designs to differentiate between genetic and environmental influences on health and on emerging applications of twins in multiple areas of medical research. We finish by describing how twin registries and networks are accelerating twin research worldwide.
dc.languageEnglish
dc.publisherCAMBRIDGE UNIV PRESS
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.titleThe Value of Twins for Health and Medical Research: A Third of a Century of Progress
dc.typeJournal Article
dc.identifier.doi10.1017/thg.2020.4
melbourne.affiliation.departmentPaediatrics (RCH)
melbourne.affiliation.departmentObstetrics and Gynaecology
melbourne.affiliation.departmentMelbourne School of Population and Global Health
melbourne.source.titleTwin Research and Human Genetics
melbourne.source.volume23
melbourne.source.issue1
melbourne.source.pages8-15
melbourne.identifier.nhmrc1079102
dc.rights.licensecc-by
melbourne.elementsid1436580
melbourne.contributor.authorUmstad, Mark
melbourne.contributor.authorCalais Ferreira, Lucas
melbourne.contributor.authorCraig, Jeffrey
dc.identifier.eissn1839-2628
melbourne.identifier.fundernameidNHMRC, 1079102
melbourne.accessrightsOpen Access


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