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dc.contributor.authorWijeysundera, DN
dc.contributor.authorBeattie, WS
dc.contributor.authorHillis, GS
dc.contributor.authorAbbott, TEF
dc.contributor.authorShulman, MA
dc.contributor.authorAckland, GL
dc.contributor.authorMazer, CD
dc.contributor.authorMyles, PS
dc.contributor.authorPearse, RM
dc.contributor.authorCuthbertson, BH
dc.contributor.authorMeasurement of Exercise Tolerance before Surgery Study Investigators,
dc.contributor.authorMyles, PS
dc.contributor.authorShulman, MA
dc.contributor.authorWallace, S
dc.contributor.authorFarrington, C
dc.contributor.authorThompson, B
dc.contributor.authorEllis, M
dc.contributor.authorBorg, B
dc.contributor.authorKerridge, RK
dc.contributor.authorDouglas, J
dc.contributor.authorBrannan, J
dc.contributor.authorPretto, J
dc.contributor.authorGodsall, MG
dc.contributor.authorBeauchamp, N
dc.contributor.authorAllen, S
dc.contributor.authorKennedy, A
dc.contributor.authorWright, E
dc.contributor.authorMalherbe, J
dc.contributor.authorIsmail, H
dc.contributor.authorRiedel, B
dc.contributor.authorMelville, A
dc.contributor.authorSivakumar, H
dc.contributor.authorMurmane, A
dc.contributor.authorKenchington, K
dc.contributor.authorKirabiyik, Y
dc.contributor.authorGurunathan, U
dc.contributor.authorStonell, C
dc.contributor.authorBrunello, K
dc.contributor.authorSteele, K
dc.contributor.authorTronstad, O
dc.contributor.authorMasel, P
dc.contributor.authorDent, A
dc.contributor.authorSmith, E
dc.contributor.authorBodger, A
dc.contributor.authorAbolfathi, M
dc.contributor.authorSivalingam, P
dc.contributor.authorHall, A
dc.contributor.authorPainter, TW
dc.contributor.authorMacklin, S
dc.contributor.authorElliott, A
dc.contributor.authorCarrera, AM
dc.contributor.authorTerblanche, NCS
dc.contributor.authorPitt, S
dc.contributor.authorSamuels, J
dc.contributor.authorWilde, C
dc.contributor.authorLeslie, K
dc.contributor.authorMacCormick, A
dc.contributor.authorBramley, D
dc.contributor.authorSouthcott, AM
dc.contributor.authorGrant, J
dc.contributor.authorTaylor, H
dc.contributor.authorBates, S
dc.contributor.authorTowns, M
dc.contributor.authorTippett, A
dc.contributor.authorMarshall, F
dc.contributor.authorMazer, CD
dc.contributor.authorKunasingam, J
dc.contributor.authorYagnik, A
dc.contributor.authorCrescini, C
dc.contributor.authorYagnik, S
dc.contributor.authorMcCartney, CJL
dc.contributor.authorChoi, S
dc.contributor.authorSomascanthan, P
dc.contributor.authorFlores, K
dc.contributor.authorWijeysundera, DN
dc.contributor.authorBeattie, WS
dc.contributor.authorKarkouti, K
dc.contributor.authorClarke, HA
dc.contributor.authorJerath, A
dc.contributor.authorMcCluskey, SA
dc.contributor.authorWasowicz, M
dc.contributor.authorGranton, JT
dc.contributor.authorDay, L
dc.contributor.authorPazmino-Canizares, J
dc.contributor.authorOh, P
dc.contributor.authorBelliard, R
dc.contributor.authorLee, L
dc.contributor.authorDobson, K
dc.contributor.authorChan, V
dc.contributor.authorBrull, R
dc.contributor.authorAmi, N
dc.contributor.authorStanbrook, M
dc.contributor.authorHagen, K
dc.contributor.authorCampbell, D
dc.contributor.authorShort, T
dc.contributor.authorVan Der Westhuizen, J
dc.contributor.authorHiggie, K
dc.contributor.authorLindsay, H
dc.contributor.authorJang, R
dc.contributor.authorWong, C
dc.contributor.authorMcallister, D
dc.contributor.authorAli, M
dc.contributor.authorKumar, J
dc.contributor.authorWaymouth, E
dc.contributor.authorKim, C
dc.contributor.authorDimech, J
dc.contributor.authorLorimer, M
dc.contributor.authorTai, J
dc.contributor.authorMiller, R
dc.contributor.authorSara, R
dc.contributor.authorCollingwood, A
dc.contributor.authorOlliff, S
dc.contributor.authorGabriel, S
dc.contributor.authorHouston, H
dc.contributor.authorDalley, P
dc.contributor.authorHurford, S
dc.contributor.authorHunt, A
dc.contributor.authorAndrews, L
dc.contributor.authorNavarra, L
dc.contributor.authorJason-Smith, A
dc.contributor.authorThompson, H
dc.contributor.authorMcMillan, N
dc.contributor.authorBack, G
dc.contributor.authorCroal, BL
dc.contributor.authorLum, M
dc.contributor.authorMartin, D
dc.contributor.authorJames, S
dc.contributor.authorFilipe, H
dc.contributor.authorPinto, M
dc.contributor.authorKynaston, S
dc.contributor.authorPearse, RM
dc.contributor.authorAbbott, TEF
dc.contributor.authorPhull, M
dc.contributor.authorBeilstein, C
dc.contributor.authorBodger, P
dc.contributor.authorEveringham, K
dc.contributor.authorHu, Y
dc.contributor.authorNiebrzegowska, E
dc.contributor.authorCorriea, C
dc.contributor.authorCreary, T
dc.contributor.authorJanuszewska, M
dc.contributor.authorAhmad, T
dc.contributor.authorWhalley, J
dc.contributor.authorHaslop, R
dc.contributor.authorMcNeil, J
dc.contributor.authorBrown, A
dc.contributor.authorMacDonald, N
dc.contributor.authorPakats, M
dc.contributor.authorGreaves, K
dc.contributor.authorJhanji, S
dc.contributor.authorRaobaikady, R
dc.contributor.authorBlack, E
dc.contributor.authorRooms, M
dc.contributor.authorLawrence, H
dc.contributor.authorKoutra, M
dc.contributor.authorPirie, K
dc.contributor.authorGertsman, M
dc.contributor.authorJack, S
dc.contributor.authorCelinski, M
dc.contributor.authorLevett, D
dc.contributor.authorEdwards, M
dc.contributor.authorSalmon, K
dc.contributor.authorBolger, C
dc.contributor.authorLoughney, L
dc.contributor.authorSeaward, L
dc.contributor.authorCollins, H
dc.contributor.authorTyrell, B
dc.contributor.authorTantony, N
dc.contributor.authorGolder, K
dc.contributor.authorAckland, GL
dc.contributor.authorStephens, RCM
dc.contributor.authorGallego-Paredes, L
dc.contributor.authorReyes, A
dc.contributor.authorGutierrez Del Arroyo, A
dc.contributor.authorRaj, A
dc.contributor.authorLifford, R
dc.contributor.authorInternational and National Coordinators,
dc.contributor.authorCentral Project Office Operations Committee,
dc.contributor.authorCPET Methods Committee,
dc.contributor.authorOutcome Adjudication Committee,
dc.contributor.authorInternational Steering Committee,
dc.date.accessioned2020-11-26T23:58:54Z
dc.date.available2020-11-26T23:58:54Z
dc.date.issued2020-03
dc.identifierpii: S0007-0912(19)30929-8
dc.identifier.citationWijeysundera, D. N., Beattie, W. S., Hillis, G. S., Abbott, T. E. F., Shulman, M. A., Ackland, G. L., Mazer, C. D., Myles, P. S., Pearse, R. M., Cuthbertson, B. H., Measurement of Exercise Tolerance before Surgery Study Investigators, , Myles, P. S., Shulman, M. A., Wallace, S., Farrington, C., Thompson, B., Ellis, M., Borg, B., Kerridge, R. K. ,... International Steering Committee, (2020). Integration of the Duke Activity Status Index into preoperative risk evaluation: a multicentre prospective cohort study.. Br J Anaesth, 124 (3), pp.261-270. https://doi.org/10.1016/j.bja.2019.11.025.
dc.identifier.issn0007-0912
dc.identifier.urihttp://hdl.handle.net/11343/252305
dc.description.abstractBACKGROUND: The Duke Activity Status Index (DASI) questionnaire might help incorporate self-reported functional capacity into preoperative risk assessment. Nonetheless, prognostically important thresholds in DASI scores remain unclear. We conducted a nested cohort analysis of the Measurement of Exercise Tolerance before Surgery (METS) study to characterise the association of preoperative DASI scores with postoperative death or complications. METHODS: The analysis included 1546 participants (≥40 yr of age) at an elevated cardiac risk who had inpatient noncardiac surgery. The primary outcome was 30-day death or myocardial injury. The secondary outcomes were 30-day death or myocardial infarction, in-hospital moderate-to-severe complications, and 1 yr death or new disability. Multivariable logistic regression modelling was used to characterise the adjusted association of preoperative DASI scores with outcomes. RESULTS: The DASI score had non-linear associations with outcomes. Self-reported functional capacity better than a DASI score of 34 was associated with reduced odds of 30-day death or myocardial injury (odds ratio: 0.97 per 1 point increase above 34; 95% confidence interval [CI]: 0.96-0.99) and 1 yr death or new disability (odds ratio: 0.96 per 1 point increase above 34; 95% CI: 0.92-0.99). Self-reported functional capacity worse than a DASI score of 34 was associated with increased odds of 30-day death or myocardial infarction (odds ratio: 1.05 per 1 point decrease below 34; 95% CI: 1.00-1.09), and moderate-to-severe complications (odds ratio: 1.03 per 1 point decrease below 34; 95% CI: 1.01-1.05). CONCLUSIONS: A DASI score of 34 represents a threshold for identifying patients at risk for myocardial injury, myocardial infarction, moderate-to-severe complications, and new disability.
dc.languageeng
dc.publisherElsevier BV
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0
dc.titleIntegration of the Duke Activity Status Index into preoperative risk evaluation: a multicentre prospective cohort study.
dc.typeJournal Article
dc.identifier.doi10.1016/j.bja.2019.11.025
melbourne.affiliation.departmentClinical Pathology
melbourne.affiliation.departmentMedicine, Western Health
melbourne.affiliation.departmentCritical Care
melbourne.affiliation.facultyMedicine, Dentistry & Health Sciences
melbourne.source.titleBritish Journal of Anaesthesia
melbourne.source.volume124
melbourne.source.issue3
melbourne.source.pages261-270
dc.rights.licensecc-by-nc-nd
melbourne.elementsid1427978
melbourne.contributor.authorSouthcott, Ann Marie
melbourne.contributor.authorLeslie, Kate
melbourne.contributor.authorThompson, Bryony
dc.identifier.eissn1471-6771
melbourne.accessrightsOpen Access


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