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dc.contributor.authorSouter, MNT
dc.contributor.authorEckle, SBG
dc.date.accessioned2020-11-27T00:42:30Z
dc.date.available2020-11-27T00:42:30Z
dc.date.issued2020-08-18
dc.identifier.citationSouter, M. N. T. & Eckle, S. B. G. (2020). Biased MAIT TCR Usage Poised for Limited Antigen Diversity?. FRONTIERS IN IMMUNOLOGY, 11, https://doi.org/10.3389/fimmu.2020.01845.
dc.identifier.issn1664-3224
dc.identifier.urihttp://hdl.handle.net/11343/252562
dc.description.abstractMucosal-associated invariant T (MAIT) cells are a subset of unconventional T cells that recognize the evolutionarily conserved major histocompatibility complex (MHC) class I-like antigen-presenting molecule known as MHC class I related protein 1 (MR1). Since their rise from obscurity in the early 1990s, the study of MAIT cells has grown substantially, accelerating our fundamental understanding of these cells and their possible roles in immunity. In the context of recent advances, we review here the relationship between MR1, antigen, and TCR usage among MAIT and other MR1-reactive T cells and provide a speculative discussion.
dc.languageEnglish
dc.publisherFRONTIERS MEDIA SA
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.titleBiased MAIT TCR Usage Poised for Limited Antigen Diversity?
dc.typeJournal Article
dc.identifier.doi10.3389/fimmu.2020.01845
melbourne.affiliation.departmentMicrobiology and Immunology
melbourne.source.titleFrontiers in Immunology
melbourne.source.volume11
dc.rights.licenseCC BY
melbourne.elementsid1464670
melbourne.contributor.authorEckle, Sidonia
melbourne.contributor.authorSouter, Michael
dc.identifier.eissn1664-3224
melbourne.accessrightsOpen Access


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