Show simple item record

dc.contributor.authorGhilas, S
dc.contributor.authorValencia-Hernandez, A-M
dc.contributor.authorEnders, MH
dc.contributor.authorHeath, WR
dc.contributor.authorFernandez-Ruiz, D
dc.date.accessioned2020-12-09T22:33:49Z
dc.date.available2020-12-09T22:33:49Z
dc.date.issued2020-11-01
dc.identifierpii: ijms21228565
dc.identifier.citationGhilas, S., Valencia-Hernandez, A. -M., Enders, M. H., Heath, W. R. & Fernandez-Ruiz, D. (2020). Resident Memory T Cells and Their Role within the Liver. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21 (22), https://doi.org/10.3390/ijms21228565.
dc.identifier.issn1422-0067
dc.identifier.urihttp://hdl.handle.net/11343/253002
dc.description.abstractImmunological memory is fundamental to maintain immunity against re-invading pathogens. It is the basis for prolonged protection induced by vaccines and can be mediated by humoral or cellular responses-the latter largely mediated by T cells. Memory T cells belong to different subsets with specialized functions and distributions within the body. They can be broadly separated into circulating memory cells, which pace the entire body through the lymphatics and blood, and tissue-resident memory T (TRM) cells, which are constrained to peripheral tissues. Retained in the tissues where they form, TRM cells provide a frontline defense against reinfection. Here, we review this population of cells with specific attention to the liver, where TRM cells have been found to protect against infections, in particular those by Plasmodium species that cause malaria.
dc.languageEnglish
dc.publisherMDPI
dc.titleResident Memory T Cells and Their Role within the Liver
dc.typeJournal Article
dc.identifier.doi10.3390/ijms21228565
melbourne.affiliation.departmentMicrobiology and Immunology
melbourne.affiliation.department
melbourne.source.titleInternational Journal of Molecular Sciences
melbourne.source.volume21
melbourne.source.issue22
melbourne.source.pages1-15
dc.rights.licenseCC BY
melbourne.elementsid1480237
melbourne.openaccess.pmchttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696659
melbourne.contributor.authorHeath, William
melbourne.contributor.authorGhilas, Sonia
melbourne.contributor.authorValencia Hernandez, Ana Maria
dc.identifier.eissn1422-0067
melbourne.accessrightsOpen Access


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record