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    Superinfection Exclusion in Mosquitoes and Its Potential as an Arbovirus Control Strategy

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    Author
    Laureti, M; Paradkar, PN; Fazakerley, JK; Rodriguez-Andres, J
    Date
    2020-11-01
    Source Title
    Viruses
    Publisher
    MDPI
    University of Melbourne Author/s
    Fazakerley, John; Rodriguez-Andres, Julio
    Affiliation
    Veterinary Biosciences
    Metadata
    Show full item record
    Document Type
    Journal Article
    Citations
    Laureti, M., Paradkar, P. N., Fazakerley, J. K. & Rodriguez-Andres, J. (2020). Superinfection Exclusion in Mosquitoes and Its Potential as an Arbovirus Control Strategy. VIRUSES-BASEL, 12 (11), https://doi.org/10.3390/v12111259.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/253007
    DOI
    10.3390/v12111259
    Open Access at PMC
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694488
    Abstract
    The continuing emergence of arbovirus disease outbreaks around the world, despite the use of vector control strategies, warrants the development of new strategies to reduce arbovirus transmission. Superinfection exclusion, a phenomenon whereby a primary virus infection prevents the replication of a second closely related virus, has potential to control arbovirus disease emergence and outbreaks. This phenomenon has been observed for many years in plants, insects and mammalian cells. In this review, we discuss the significance of identifying novel vector control strategies, summarize studies exploring arbovirus superinfection exclusion and consider the potential for this phenomenon to be the basis for novel arbovirus control strategies.

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