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dc.contributor.authorDuan, L
dc.contributor.authorVan Dam, NT
dc.contributor.authorAi, H
dc.contributor.authorXu, P
dc.date.accessioned2020-12-09T22:44:43Z
dc.date.available2020-12-09T22:44:43Z
dc.date.issued2020-12-20
dc.identifierpii: 10.1038/s41398-020-01088-7
dc.identifier.citationDuan, L., Van Dam, N. T., Ai, H. & Xu, P. (2020). Intrinsic organization of cortical networks predicts state anxiety: an functional near-infrared spectroscopy (fNIRS) study. TRANSLATIONAL PSYCHIATRY, 10 (1), https://doi.org/10.1038/s41398-020-01088-7.
dc.identifier.issn2158-3188
dc.identifier.urihttp://hdl.handle.net/11343/253061
dc.description.abstractAlthough state anxiety has been characterized by hyper-responsive subcortical activity and its bottom-up connectivity with cortical regions, the role of cortical networks in state anxiety is not yet well understood. To this end, we decoded individual state anxiety by using a machine-learning approach based on resting-state functional connectivity (RSFC) with functional near-infrared spectroscopy (fNIRS). Our results showed that the RSFC among a set of cortical networks were highly predictive of state anxiety, rather than trait anxiety. Specifically, these networks included connectivity between cortical areas in the default mode network (DMN) and dorsal attention network (DAN), and connectivity within the DMN, which were negatively correlated with state anxiety; connectivity between cortical areas in the DMN and frontoparietal network (FPN), FPN and salience network (SN), FPN and DAN, DMN and SN, which were positively correlated with state anxiety. These findings suggest a predictive role of intrinsic cortical organization in the assessment of state anxiety. The work provides new insights into potential neural mechanisms of emotion states and implications for prognosis, diagnosis, and treatment of affective disorders.
dc.languageEnglish
dc.publisherSPRINGERNATURE
dc.titleIntrinsic organization of cortical networks predicts state anxiety: an functional near-infrared spectroscopy (fNIRS) study
dc.typeJournal Article
dc.identifier.doi10.1038/s41398-020-01088-7
melbourne.affiliation.departmentMelbourne School of Psychological Sciences
melbourne.source.titleTranslational Psychiatry
melbourne.source.volume10
melbourne.source.issue1
dc.rights.licenseCC BY
melbourne.elementsid1482592
melbourne.contributor.authorVan Dam, Nicholas
dc.identifier.eissn2158-3188
melbourne.accessrightsOpen Access


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