COVID-3D: An online resource to explore the structural distribution of genetic variation in SARS-CoV-2 and its implication on therapeutic development

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    Author
    Portelli, S; Olshansky, M; Rodrigues, CHM; D’Souza, E; Myung, Y; Silk, M; Alavi, A; Pires, DEV; Ascher, D
    Date
    2020-05-30
    Source Title
    bioRxiv
    Publisher
    Cold Spring Harbor Laboratory
    University of Melbourne Author/s
    Ascher, David; Pires, Douglas
    Affiliation
    Biochemistry and Molecular Biology
    Metadata
    Show full item record
    Document Type
    Preprint
    Citations
    Portelli, S., Olshansky, M., Rodrigues, C. H. M., D’Souza, E., Myung, Y., Silk, M., Alavi, A., Pires, D. E. V. & Ascher, D. (2020). COVID-3D: An online resource to explore the structural distribution of genetic variation in SARS-CoV-2 and its implication on therapeutic development. bioRxiv, https://doi.org/10.1101/2020.05.29.124610.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/253067
    DOI
    10.1101/2020.05.29.124610
    NHMRC Grant code
    NHMRC/1174405
    Abstract
    <h4>SUMMARY</h4> The emergence of the COVID-19 pandemic has spurred a global rush to uncover basic biological mechanisms, to inform effective vaccine and drug development. Despite viral novelty, global sequencing efforts have already identified genomic variation across isolates. To enable easy exploration and spatial visualization of the potential implications of SARS-CoV-2 mutations on infection, host immunity and drug development we have developed COVID-3D ( http://biosig.unimelb.edu.au/covid3d/ ).

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