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  • Anatomy and Neuroscience
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    Unsupervised online neuropsychological test performance for individuals with mild cognitive impairment and dementia: Results from the Brain Health Registry.

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    10
    Author
    Mackin, RS; Insel, PS; Truran, D; Finley, S; Flenniken, D; Nosheny, R; Ulbright, A; Comacho, M; Bickford, D; Harel, B; ...
    Date
    2018
    Source Title
    Alzheimer's & dementia (Amsterdam, Netherlands)
    Publisher
    Wiley
    University of Melbourne Author/s
    Maruff, Paul
    Affiliation
    Anatomy and Neuroscience
    Metadata
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    Document Type
    Journal Article
    Citations
    Mackin, R. S., Insel, P. S., Truran, D., Finley, S., Flenniken, D., Nosheny, R., Ulbright, A., Comacho, M., Bickford, D., Harel, B., Maruff, P. & Weiner, M. W. (2018). Unsupervised online neuropsychological test performance for individuals with mild cognitive impairment and dementia: Results from the Brain Health Registry.. Alzheimers Dement (Amst), 10 (1), pp.573-582. https://doi.org/10.1016/j.dadm.2018.05.005.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/253115
    DOI
    10.1016/j.dadm.2018.05.005
    Open Access at PMC
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215059
    Abstract
    Introduction: The purpose of this study is to compare online neuropsychological test performance of older adults across self-reported diagnoses of being cognitively normal, mild cognitive impairment, and dementia due to Alzheimer's disease and to determine the association of memory concerns and family history of dementia on cognitive performance. Methods: Participants completed the Cogstate Brief Battery unsupervised at home. Results: Data from 6463 participants over the age of 55 years were analyzed. Adults with the diagnosis of mild cognitive impairment and Alzheimer's disease were associated with poorer performance on all cognitive tests than cognitively normal adults (P < .05 for all), and online cognitive test performance significantly improved diagnostic classification (P < .001). Poorer performance on all cognitive measures was associated with memory concern (P < .001 for all) but not family history of dementia. Discussion: Our results provide preliminary support for the use of cognitive tests taken online without supervision as a means to improve the efficiency of participant screening and recruitment for clinical trials.

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