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dc.contributor.authorNguyen, TA
dc.contributor.authorAbdelhamid, YA
dc.contributor.authorPhillips, LK
dc.contributor.authorChapple, LS
dc.contributor.authorHorowitz, M
dc.contributor.authorJones, KL
dc.contributor.authorDeane, AM
dc.date.accessioned2020-12-09T23:10:56Z
dc.date.available2020-12-09T23:10:56Z
dc.date.issued2017-02-04
dc.identifier.citationNguyen, T. A., Abdelhamid, Y. A., Phillips, L. K., Chapple, L. S., Horowitz, M., Jones, K. L. & Deane, A. M. (2017). Nutrient stimulation of mesenteric blood flow - implications for older critically ill patients.. World J Crit Care Med, 6 (1), pp.28-36. https://doi.org/10.5492/wjccm.v6.i1.28.
dc.identifier.issn2220-3141
dc.identifier.urihttp://hdl.handle.net/11343/253163
dc.description.abstractNutrient ingestion induces a substantial increase in mesenteric blood flow. In older persons (aged ≥ 65 years), particularly those with chronic medical conditions, the cardiovascular compensatory response may be inadequate to maintain systemic blood pressure during mesenteric blood pooling, leading to postprandial hypotension. In older ambulatory persons, postprandial hypotension is an important pathophysiological condition associated with an increased propensity for syncope, falls, coronary vascular events, stroke and death. In older critically ill patients, the administration of enteral nutrition acutely increases mesenteric blood flow, but whether this pathophysiological response is protective, or precipitates mesenteric ischaemia, is unknown. There are an increasing number of older patients surviving admission to intensive care units, who are likely to be at increased risk of postprandial hypotension, both during, and after, their stay in hospital. In this review, we describe the prevalence, impact and mechanisms of postprandial hypotension in older people and provide an overview of the impact of postprandial hypotension on feeding prescriptions in older critically ill patients. Finally, we provide evidence that postprandial hypotension is likely to be an unrecognised problem in older survivors of critical illness and discuss potential options for management.
dc.languageeng
dc.publisherBaishideng Publishing Group Inc.
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0
dc.titleNutrient stimulation of mesenteric blood flow - implications for older critically ill patients.
dc.typeJournal Article
dc.identifier.doi10.5492/wjccm.v6.i1.28
melbourne.affiliation.departmentMedicine (RMH)
melbourne.affiliation.departmentCritical Care
melbourne.affiliation.facultyMedicine, Dentistry & Health Sciences
melbourne.source.titleWorld Journal of Critical Care Medicine
melbourne.source.volume6
melbourne.source.issue1
melbourne.source.pages28-36
dc.rights.licenseCC BY-NC
melbourne.elementsid1353721
melbourne.openaccess.pmchttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295167
melbourne.contributor.authorDeane, Adam
melbourne.contributor.authorAli Abdelhamid, Yasmine
dc.identifier.eissn2220-3141
melbourne.accessrightsOpen Access


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