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dc.contributor.authorButtery, S
dc.contributor.authorKemp, SV
dc.contributor.authorShah, PL
dc.contributor.authorWaller, D
dc.contributor.authorJordan, S
dc.contributor.authorLee, JT
dc.contributor.authorBanya, W
dc.contributor.authorSteiner, MC
dc.contributor.authorHopkinson, NS
dc.date.accessioned2020-12-09T23:40:15Z
dc.date.available2020-12-09T23:40:15Z
dc.date.issued2018-10-01
dc.identifierpii: bmjopen-2017-021368
dc.identifier.citationButtery, S., Kemp, S. V., Shah, P. L., Waller, D., Jordan, S., Lee, J. T., Banya, W., Steiner, M. C. & Hopkinson, N. S. (2018). CELEB trial: Comparative Effectiveness of Lung volume reduction surgery for Emphysema and Bronchoscopic lung volume reduction with valve placement: a protocol for a randomised controlled trial. BMJ Open, 8 (10), https://doi.org/10.1136/bmjopen-2017-021368.
dc.identifier.issn2044-6055
dc.identifier.urihttp://hdl.handle.net/11343/253293
dc.description.abstractINTRODUCTION: Although lung volume reduction surgery and bronchoscopic lung volume reduction with endobronchial valves have both been shown to improve lung function, exercise capacity and quality of life in appropriately selected patients with emphysema, there are no direct comparison data between the two procedures to inform clinical decision-making. METHODS AND ANALYSIS: We describe the protocol of the CELEB study, a randomised controlled trial which will compare outcomes at 1 year between the two procedures, using a composite disease severity measure, the iBODE score, which includes body mass index, airflow obstruction, dyspnoeaand exercise capacity (incremental shuttle walk test). ETHICS AND DISSEMINATION: Ethical approval to conduct the study has been obtained from the Fulham Research Ethics Committee, London (16/LO/0286). The outcome of this trial will provide information to guide treatment choices in this population and will be presented at national and international meetings and published in peer-reviewed journals. We will also disseminate the main results to all participants in a letter. TRIAL REGISTRATION NUMBER: ISRCTN19684749; Pre-results.
dc.languageEnglish
dc.publisherBMJ Journals
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.titleCELEB trial: Comparative Effectiveness of Lung volume reduction surgery for Emphysema and Bronchoscopic lung volume reduction with valve placement: a protocol for a randomised controlled trial
dc.typeJournal Article
dc.identifier.doi10.1136/bmjopen-2017-021368
melbourne.affiliation.departmentMelbourne School of Population and Global Health
melbourne.source.titleBMJ Open
melbourne.source.volume8
melbourne.source.issue10
dc.rights.licenseCC BY
melbourne.elementsid1354907
melbourne.contributor.authorLee, Ta-Yu
dc.identifier.eissn2044-6055
melbourne.accessrightsOpen Access


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