dc.contributor.author | Hurley, JC | |
dc.date.accessioned | 2020-12-09T23:50:46Z | |
dc.date.available | 2020-12-09T23:50:46Z | |
dc.date.issued | 2018-03-01 | |
dc.identifier | pii: microorganisms6010018 | |
dc.identifier.citation | Hurley, J. C. (2018). World-Wide Variation in Incidence of Staphylococcus aureus Associated Ventilator-Associated Pneumonia: A Meta-Regression. MICROORGANISMS, 6 (1), https://doi.org/10.3390/microorganisms6010018. | |
dc.identifier.issn | 2076-2607 | |
dc.identifier.uri | http://hdl.handle.net/11343/253340 | |
dc.description.abstract | Staphylococcus aureus (S. aureus) is a common Ventilator-Associated Pneumonia (VAP) isolate. The objective here is to define the extent and possible reasons for geographic variation in the incidences of S. aureus-associated VAP, MRSA-VAP and overall VAP. A meta-regression model of S. aureus-associated VAP incidence per 1000 Mechanical Ventilation Days (MVD) was undertaken using random effects methods among publications obtained from a search of the English language literature. This model incorporated group level factors such as admission to a trauma ICU, year of publication and use of bronchoscopic sampling towards VAP diagnosis. The search identified 133 publications from seven worldwide regions published over three decades. The summary S. aureus-associated VAP incidence was 4.5 (3.9-5.3) per 1000 MVD. The highest S. aureus-associated VAP incidence is amongst reports from the Mediterranean (mean; 95% confidence interval; 6.1; 4.1-8.5) versus that from Asian ICUs (2.1; 1.5-3.0). The incidence of S. aureus-associated VAP varies by up to three-fold (for the lowest versus highest incidence) among seven geographic regions worldwide, whereas the incidence of VAP varies by less than two-fold. Admission to a trauma unit is the most important group level correlate for S. aureus-associated VAP. | |
dc.language | English | |
dc.publisher | MDPI | |
dc.title | World-Wide Variation in Incidence of Staphylococcus aureus Associated Ventilator-Associated Pneumonia: A Meta-Regression | |
dc.type | Journal Article | |
dc.identifier.doi | 10.3390/microorganisms6010018 | |
melbourne.affiliation.department | Rural Clinical School | |
melbourne.source.title | Microorganisms | |
melbourne.source.volume | 6 | |
melbourne.source.issue | 1 | |
dc.rights.license | CC BY | |
melbourne.elementsid | 1310995 | |
melbourne.contributor.author | Hurley, James | |
dc.identifier.eissn | 2076-2607 | |
melbourne.accessrights | Open Access | |