Multiplicity of Infection Is a Poor Predictor of Village-Level Plasmodium vivax and P. falciparum Population Prevalence in the Southwest Pacific

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    Author
    Koepfli, C; Waltmann, A; Ome-Kaius, M; Robinson, LJ; Mueller, I
    Date
    2018-11-01
    Source Title
    Open Forum Infectious Diseases
    Publisher
    OXFORD UNIV PRESS INC
    University of Melbourne Author/s
    Robinson, Leanne; Mueller, Ivo; Ome-Kaius, Maria
    Affiliation
    Medical Biology (W.E.H.I.)
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    Document Type
    Journal Article
    Citations
    Koepfli, C., Waltmann, A., Ome-Kaius, M., Robinson, L. J. & Mueller, I. (2018). Multiplicity of Infection Is a Poor Predictor of Village-Level Plasmodium vivax and P. falciparum Population Prevalence in the Southwest Pacific. OPEN FORUM INFECTIOUS DISEASES, 5 (11), https://doi.org/10.1093/ofid/ofy240.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/253348
    DOI
    10.1093/ofid/ofy240
    Abstract
    Across 8101 individuals in 46 villages, the proportion of Plasmodium spp. multiple clone infections (0%-53.8%) did not reflect prevalence by quantitative polymerase chain reaction (qPCR; 1.9%-38.4%), except for P. vivax in Solomon Islands (P < .001). Thus this parameter was not informative to identify transmission foci. In contrast, prevalence by microscopy and qPCR correlated well.

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