Multiplicity of Infection Is a Poor Predictor of Village-Level Plasmodium vivax and P. falciparum Population Prevalence in the Southwest Pacific

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Koepfli, C; Waltmann, A; Ome-Kaius, M; Robinson, LJ; Mueller, IDate
2018-11-01Source Title
Open Forum Infectious DiseasesPublisher
OXFORD UNIV PRESS INCAffiliation
Medical Biology (W.E.H.I.)Metadata
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Koepfli, C., Waltmann, A., Ome-Kaius, M., Robinson, L. J. & Mueller, I. (2018). Multiplicity of Infection Is a Poor Predictor of Village-Level Plasmodium vivax and P. falciparum Population Prevalence in the Southwest Pacific. OPEN FORUM INFECTIOUS DISEASES, 5 (11), https://doi.org/10.1093/ofid/ofy240.Access Status
Open AccessAbstract
Across 8101 individuals in 46 villages, the proportion of Plasmodium spp. multiple clone infections (0%-53.8%) did not reflect prevalence by quantitative polymerase chain reaction (qPCR; 1.9%-38.4%), except for P. vivax in Solomon Islands (P < .001). Thus this parameter was not informative to identify transmission foci. In contrast, prevalence by microscopy and qPCR correlated well.
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