The Safety and Efficacy of an Oral Penicillin Challenge Program in Cancer Patients: A Multicenter Pilot Study
AuthorTrubiano, JA; Smibert, O; Douglas, A; Devchand, M; Lambros, B; Holmes, NE; Chua, KY; Phillips, EJ; Slavin, MA
Source TitleOpen Forum Infectious Diseases
PublisherOXFORD UNIV PRESS INC
AffiliationMicrobiology and Immunology
Medicine (Austin & Northern Health)
Document TypeJournal Article
CitationsTrubiano, J. A., Smibert, O., Douglas, A., Devchand, M., Lambros, B., Holmes, N. E., Chua, K. Y., Phillips, E. J. & Slavin, M. A. (2018). The Safety and Efficacy of an Oral Penicillin Challenge Program in Cancer Patients: A Multicenter Pilot Study. OPEN FORUM INFECTIOUS DISEASES, 5 (12), https://doi.org/10.1093/ofid/ofy306.
Access StatusOpen Access
Antibiotic allergies are reported by up to 1 in 4 cancer patients, almost 50% of which are considered low risk and precede the cancer diagnosis. We demonstrate the successful and safe implementation of a pilot oral penicillin challenge program for cancer patients with low-risk penicillin allergies, increasing the use of penicillin and narrow-spectrum beta-lactams post-testing.
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