Latin Americans show wide-spread Converso ancestry and imprint of local Native ancestry on physical appearance

Download
Author
Chacon-Duque, J-C; Adhikari, K; Fuentes-Guajardo, M; Mendoza-Revilla, J; Acuna-Alonzo, V; Barquera, R; Quinto-Sanchez, M; Gomez-Valdes, J; Everardo Martinez, P; Villamil-Ramirez, H; ...Date
2018-12-19Source Title
Nature CommunicationsPublisher
NATURE PUBLISHING GROUPUniversity of Melbourne Author/s
Balding, DavidAffiliation
School of Mathematics and StatisticsMetadata
Show full item recordDocument Type
Journal ArticleCitations
Chacon-Duque, J. -C., Adhikari, K., Fuentes-Guajardo, M., Mendoza-Revilla, J., Acuna-Alonzo, V., Barquera, R., Quinto-Sanchez, M., Gomez-Valdes, J., Everardo Martinez, P., Villamil-Ramirez, H., Hunemeier, T., Ramallo, V., Silva de Cerqueira, C. C., Hurtado, M., Villegas, V., Granja, V., Villena, M., Vasquez, R., Llop, E. ,... Ruiz-Linares, A. (2018). Latin Americans show wide-spread Converso ancestry and imprint of local Native ancestry on physical appearance. NATURE COMMUNICATIONS, 9 (1), https://doi.org/10.1038/s41467-018-07748-z.Access Status
Open AccessAbstract
Historical records and genetic analyses indicate that Latin Americans trace their ancestry mainly to the intermixing (admixture) of Native Americans, Europeans and Sub-Saharan Africans. Using novel haplotype-based methods, here we infer sub-continental ancestry in over 6,500 Latin Americans and evaluate the impact of regional ancestry variation on physical appearance. We find that Native American ancestry components in Latin Americans correspond geographically to the present-day genetic structure of Native groups, and that sources of non-Native ancestry, and admixture timings, match documented migratory flows. We also detect South/East Mediterranean ancestry across Latin America, probably stemming mostly from the clandestine colonial migration of Christian converts of non-European origin (Conversos). Furthermore, we find that ancestry related to highland (Central Andean) versus lowland (Mapuche) Natives is associated with variation in facial features, particularly nose morphology, and detect significant differences in allele frequencies between these groups at loci previously associated with nose morphology in this sample.
Export Reference in RIS Format
Endnote
- Click on "Export Reference in RIS Format" and choose "open with... Endnote".
Refworks
- Click on "Export Reference in RIS Format". Login to Refworks, go to References => Import References