University Library
  • Login
A gateway to Melbourne's research publications
Minerva Access is the University's Institutional Repository. It aims to collect, preserve, and showcase the intellectual output of staff and students of the University of Melbourne for a global audience.
View Item 
  • Minerva Access
  • Medicine, Dentistry & Health Sciences
  • Melbourne School of Population and Global Health
  • Melbourne School of Population and Global Health - Research Publications
  • View Item
  • Minerva Access
  • Medicine, Dentistry & Health Sciences
  • Melbourne School of Population and Global Health
  • Melbourne School of Population and Global Health - Research Publications
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

    A Divergent Hepatitis D-Like Agent in Birds

    Thumbnail
    Download
    Published version (4.998Mb)

    Citations
    Scopus
    Web of Science
    Altmetric
    16
    18
    Author
    Wille, M; Netter, HJ; Littlejohn, M; Yuen, L; Shi, M; Eden, J-S; Klaassen, M; Holmes, EC; Hurt, AC
    Date
    2018-12-01
    Source Title
    Viruses
    Publisher
    MDPI
    University of Melbourne Author/s
    Littlejohn, Margaret; Hurt, Aeron
    Affiliation
    Melbourne School of Population and Global Health
    Doherty Institute
    Metadata
    Show full item record
    Document Type
    Journal Article
    Citations
    Wille, M., Netter, H. J., Littlejohn, M., Yuen, L., Shi, M., Eden, J. -S., Klaassen, M., Holmes, E. C. & Hurt, A. C. (2018). A Divergent Hepatitis D-Like Agent in Birds. VIRUSES-BASEL, 10 (12), https://doi.org/10.3390/v10120720.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/253624
    DOI
    10.3390/v10120720
    Abstract
    Hepatitis delta virus (HDV) is currently only found in humans and is a satellite virus that depends on hepatitis B virus (HBV) envelope proteins for assembly, release, and entry. Using meta-transcriptomics, we identified the genome of a novel HDV-like agent in ducks. Sequence analysis revealed secondary structures that were shared with HDV, including self-complementarity and ribozyme features. The predicted viral protein shares 32% amino acid similarity to the small delta antigen of HDV and comprises a divergent phylogenetic lineage. The discovery of an avian HDV-like agent has important implications for the understanding of the origins of HDV and sub-viral agents.

    Export Reference in RIS Format     

    Endnote

    • Click on "Export Reference in RIS Format" and choose "open with... Endnote".

    Refworks

    • Click on "Export Reference in RIS Format". Login to Refworks, go to References => Import References


    Collections
    • Minerva Elements Records [53039]
    • Doherty Institute - Research Publications [374]
    • Melbourne School of Population and Global Health - Research Publications [5329]
    Minerva AccessDepositing Your Work (for University of Melbourne Staff and Students)NewsFAQs

    BrowseCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects
    My AccountLoginRegister
    StatisticsMost Popular ItemsStatistics by CountryMost Popular Authors