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dc.contributor.authorSinghania, R
dc.contributor.authorKhairuddin, N
dc.contributor.authorClarke, D
dc.contributor.authorMcMillan, NA
dc.date.accessioned2020-12-10T01:25:15Z
dc.date.available2020-12-10T01:25:15Z
dc.date.issued2012
dc.identifierpii: TOVJ-6-204
dc.identifier.citationSinghania, R., Khairuddin, N., Clarke, D. & McMillan, N. A. (2012). RNA interference for the treatment of papillomavirus disease.. Open Virol J, 6 (1), pp.204-215. https://doi.org/10.2174/1874357901206010204.
dc.identifier.issn1874-3579
dc.identifier.urihttp://hdl.handle.net/11343/253700
dc.description.abstractHuman Papillomavirus (HPV)-induced diseases are a significant burden on our healthcare system and current therapies are not curative. Vaccination provides significant prophylactic protection but effective therapeutic treatments will still be required. RNA interference (RNAi) has great promise in providing highly specific therapies for all HPV diseases yet this promise has not been realised. Here we review the research into RNAi therapy for HPV in vitro and in vivo and examine the various targets and outcomes. We discuss the idea of using RNAi with current treatments and address delivery of RNAi, the major issue holding back clinical adoption. Finally, we present our view of a potential path to the clinic.
dc.languageeng
dc.publisherBentham Science Publishers Ltd.
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0
dc.titleRNA interference for the treatment of papillomavirus disease.
dc.typeJournal Article
dc.identifier.doi10.2174/1874357901206010204
melbourne.affiliation.departmentMicrobiology and Immunology
melbourne.source.titleOpen Virology Journal
melbourne.source.volume6
melbourne.source.issue1
melbourne.source.pages204-215
dc.rights.licenseCC BY-NC
melbourne.elementsid1371015
melbourne.openaccess.pmchttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547394
melbourne.contributor.authorClarke, Daniel
dc.identifier.eissn1874-3579
melbourne.accessrightsOpen Access


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