A child with Klinefelter syndrome and both IgE-mediated food allergy and low proportion of naive Treg
AuthorFrederick, R; Vuillermin, P; Tang, MLK; Ponsonby, A-L; Webster, E; Saffery, R; Collier, F
Source TitleClinical Case Reports
University of Melbourne Author/sPonsonby, Anne-Louise; Vuillermin, Peter; Saffery, Richard; Tang, Mimi; COLLIER, FIONA MCLEOD
AffiliationMelbourne School of Population and Global Health
Document TypeJournal Article
CitationsFrederick, R., Vuillermin, P., Tang, M. L. K., Ponsonby, A. -L., Webster, E., Saffery, R. & Collier, F. (2019). A child with Klinefelter syndrome and both IgE-mediated food allergy and low proportion of naive Treg. CLINICAL CASE REPORTS, 7 (2), pp.302-303. https://doi.org/10.1002/ccr3.1928.
Access StatusOpen Access
This case suggests a possible association between Klinefelter Syndrome and decreased regulatory T cells (Treg) cells, relating to an increased risk of allergic and autoimmune disorders in these patients. The immune phenotyping of the circulating FOXP3+ naive Treg populations in KS patients may help to indicate this predisposition.
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