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dc.contributor.authorKe, PC
dc.contributor.authorPilkington, EH
dc.contributor.authorSun, Y
dc.contributor.authorJaved, I
dc.contributor.authorKakinen, A
dc.contributor.authorPeng, G
dc.contributor.authorDing, F
dc.contributor.authorDavis, TP
dc.date.accessioned2020-12-10T03:19:20Z
dc.date.available2020-12-10T03:19:20Z
dc.date.issued2020-05
dc.identifier.citationKe, P. C., Pilkington, E. H., Sun, Y., Javed, I., Kakinen, A., Peng, G., Ding, F. & Davis, T. P. (2020). Mitigation of Amyloidosis with Nanomaterials.. Adv Mater, 32 (18), pp.e1901690-. https://doi.org/10.1002/adma.201901690.
dc.identifier.issn0935-9648
dc.identifier.urihttp://hdl.handle.net/11343/253831
dc.description.abstractAmyloidosis is a biophysical phenomenon of protein aggregation with biological and pathogenic implications. Among the various strategies developed to date, nanomaterials and multifunctional nanocomposites possessing certain structural and physicochemical traits are promising candidates for mitigating amyloidosis in vitro and in vivo. The mechanisms underpinning protein aggregation and toxicity are introduced, and opportunities in materials science to drive this interdisciplinary field forward are highlighted. Advancement of this emerging frontier hinges on exploitation of protein self-assembly and interactions of amyloid proteins with nanoparticles, intracellular and extracellular proteins, chaperones, membranes, organelles, and biometals.
dc.languageeng
dc.publisherWiley
dc.titleMitigation of Amyloidosis with Nanomaterials.
dc.typeJournal Article
dc.identifier.doi10.1002/adma.201901690
melbourne.affiliation.departmentMicrobiology and Immunology
melbourne.source.titleAdvanced Materials
melbourne.source.volume32
melbourne.source.issue18
melbourne.source.pagese1901690-
melbourne.elementsid1436315
melbourne.openaccess.urlhttps://rss.onlinelibrary.wiley.com/doi/am-pdf/10.1002/adma.201901690
melbourne.openaccess.pmchttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904546
melbourne.openaccess.statusAccepted version
melbourne.contributor.authorPilkington, Emily
dc.identifier.eissn1521-4095
melbourne.accessrightsOpen Access


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