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    Whitepaper: Defining and investigating cognitive reserve, brain reserve, and brain maintenance.

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    132
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    Author
    Stern, Y; Arenaza-Urquijo, EM; Bartrés-Faz, D; Belleville, S; Cantilon, M; Chetelat, G; Ewers, M; Franzmeier, N; Kempermann, G; Kremen, WS; ...
    Date
    2020-09
    Source Title
    Alzheimer's and Dementia
    Publisher
    Wiley
    University of Melbourne Author/s
    Lim, Yen Ying
    Affiliation
    Florey Department of Neuroscience and Mental Health
    Metadata
    Show full item record
    Document Type
    Journal Article
    Citations
    Stern, Y., Arenaza-Urquijo, E. M., Bartrés-Faz, D., Belleville, S., Cantilon, M., Chetelat, G., Ewers, M., Franzmeier, N., Kempermann, G., Kremen, W. S., Okonkwo, O., Scarmeas, N., Soldan, A., Udeh-Momoh, C., Valenzuela, M., Vemuri, P., Vuoksimaa, E. & the Reserve, Resilience and Protective Factors PIA Empirical Definitions and Conceptual Frameworks Workgroup (2020). Whitepaper: Defining and investigating cognitive reserve, brain reserve, and brain maintenance.. Alzheimers Dement, 16 (9), pp.1305-1311. https://doi.org/10.1016/j.jalz.2018.07.219.
    Access Status
    Access this item via the Open Access location
    URI
    http://hdl.handle.net/11343/253910
    DOI
    10.1016/j.jalz.2018.07.219
    Open Access URL
    http://europepmc.org/articles/pmc6417987?pdf=render
    Open Access at PMC
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417987
    Abstract
    Several concepts, which in the aggregate get might be used to account for "resilience" against age- and disease-related changes, have been the subject of much research. These include brain reserve, cognitive reserve, and brain maintenance. However, different investigators have use these terms in different ways, and there has never been an attempt to arrive at consensus on the definition of these concepts. Furthermore, there has been confusion regarding the measurement of these constructs and the appropriate ways to apply them to research. Therefore the reserve, resilience, and protective factors professional interest area, established under the auspices of the Alzheimer's Association, established a whitepaper workgroup to develop consensus definitions for cognitive reserve, brain reserve, and brain maintenance. The workgroup also evaluated measures that have been used to implement these concepts in research settings and developed guidelines for research that explores or utilizes these concepts. The workgroup hopes that this whitepaper will form a reference point for researchers in this area and facilitate research by supplying a common language.

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