Audiology and Speech Pathology - Research Publications

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Can we detect altered disease state in early stage Huntington’s Disease using acoustic markers of speech?

Vogel, A. P.; Shirbin, C.; Churchyard, A. J.; Stout, J. C. (Causal Productions, 2012)

Altered prosody has been described in symptomatic Huntington’s Disease (HD) individuals, however, the extent to which acoustic analysis of speech is sensitive to gene positive pre-manifest (PreHD) individuals is unknown. ...

Acoustic analysis of the effects of 24 hours of sustained wakefulness

Vogel, Adam P.; FLETCHER, JANET; MARUFF, PAUL (Causal Productions, 2010)

The effect of 24 hours of sustained wakefulness on the speech of healthy adults is poorly documented. Therefore, speech samples were systematically acquired (e.g., every four hours) from 18 healthy adults over 24 hours. ...

Dysphagia and swallowing-related quality of life in Friedreich ataxia

Vogel, Adam P.; Brown, Sophie E.; Folker, Joanne E.; Corben, Louise A.; Delatycki, Martin B. (Springer, 2014)

Dysphagia in Friedreich ataxia (FRDA) and its impact on quality of life is not adequately understood. The objective of this study was to characterise dysphagia in FRDA and to determine the impact of swallowing dysfunction ...

Speech acoustic markers of early stage and prodromal Huntington's disease: A marker of disease onset?

Vogel, AP; Shirbin, C; Churchyard, AJ; Stout, JC (PERGAMON-ELSEVIER SCIENCE LTD, 2012-12-01)

Speech disturbances (e.g., altered prosody) have been described in symptomatic Huntington's Disease (HD) individuals, however, the extent to which speech changes in gene positive pre-manifest (PreHD) individuals is largely ...

Logopenic and Nonfluent Variants of Primary Progressive Aphasia Are Differentiated by Acoustic Measures of Speech Production

Ballard, KJ; Savage, S; Leyton, CE; Vogel, AP; Hornberger, M; Hodges, JR (PUBLIC LIBRARY SCIENCE, 2014-02-28)

Differentiation of logopenic (lvPPA) and nonfluent/agrammatic (nfvPPA) variants of Primary Progressive Aphasia is important yet remains challenging since it hinges on expert based evaluation of speech and language production. ...

Innervation of Cochlear Hair Cells by Human Induced Pluripotent Stem Cell-Derived Neurons In Vitro

Gunewardene, N; Crombie, D; Dottori, M; Nayagam, BA (HINDAWI PUBLISHING CORP, 2016-01-01)

Induced pluripotent stem cells (iPSCs) may serve as an autologous source of replacement neurons in the injured cochlea, if they can be successfully differentiated and reconnected with residual elements in the damaged ...

Enriched retinal ganglion cells derived from human embryonic stem cells

Gill, KP; Hung, SSC; Sharov, A; Lo, CY; Needham, K; Lidgerwood, GE; Jackson, S; Crombie, DE; Nayagam, BA; Cook, AL; ... (NATURE PUBLISHING GROUP, 2016-08-10)

Optic neuropathies are characterised by a loss of retinal ganglion cells (RGCs) that lead to vision impairment. Development of cell therapy requires a better understanding of the signals that direct stem cells into RGCs. ...

Parenting Stress in Parents of Children With Cochlear Implants: Relationships Among Parent Stress, Child Language, and Unilateral Versus Bilateral Implants

Sarant, J; Garrard, P (OXFORD UNIV PRESS, 2014-01-01)

Little attention has been focused on stress levels of parents of children with cochlear implants (CIs). This study examined the stress experience of 70 parents of children with CIs by comparing stress levels in this group ...

Achievement of early clinical milestones and long-term functional outcomes for children and young adults with bilateral cochlear implants.

Galvin, KL (2015-01)

Adapting to bilateral cochlear implants: early post-operative device use by children receiving sequential or simultaneous implants at or before 3.5 years.

Galvin, KL; Hughes, KC (2012-05)

OBJECTIVE: To classify adaptation difficulties, or lack thereof, experienced by a clinical population of young bilateral cochlear implant recipients. METHOD: Forty-six of the first 48 children sequentially or simultaneously ...

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