Audiology and Speech Pathology - Research Publications
Now showing items 1-10 of 56
Can we detect altered disease state in early stage Huntington’s Disease using acoustic markers of speech?
(Causal Productions, 2012)
Altered prosody has been described in symptomatic Huntington’s Disease (HD) individuals, however, the extent to which acoustic analysis of speech is sensitive to gene positive pre-manifest (PreHD) individuals is unknown. ...
Acoustic analysis of the effects of 24 hours of sustained wakefulness
(Causal Productions, 2010)
The effect of 24 hours of sustained wakefulness on the speech of healthy adults is poorly documented. Therefore, speech samples were systematically acquired (e.g., every four hours) from 18 healthy adults over 24 hours. ...
Dysphagia and swallowing-related quality of life in Friedreich ataxia
Dysphagia in Friedreich ataxia (FRDA) and its impact on quality of life is not adequately understood. The objective of this study was to characterise dysphagia in FRDA and to determine the impact of swallowing dysfunction ...
Dysphagia in spinocerebellar ataxia and multiple system atrophy-cerebellar
(Maney Publishing, 2015)
Vocal Acoustic Biomarkers of Depression Severity and Treatment Response
(ELSEVIER SCIENCE INC, 2012-10-01)
BACKGROUND: Valid, reliable biomarkers of depression severity and treatment response would provide new targets for clinical research. Noticeable differences in speech production between depressed and nondepressed patients ...
A PATIENT'S JOURNEY Friedreich ataxia
(BMJ PUBLISHING GROUP, 2013-12-03)
Logopenic and Nonfluent Variants of Primary Progressive Aphasia Are Differentiated by Acoustic Measures of Speech Production
(PUBLIC LIBRARY SCIENCE, 2014-02-28)
Differentiation of logopenic (lvPPA) and nonfluent/agrammatic (nfvPPA) variants of Primary Progressive Aphasia is important yet remains challenging since it hinges on expert based evaluation of speech and language production. ...
Monitoring change requires a rethink of assessment practices in voice and speech
(TAYLOR & FRANCIS LTD, 2014-07-01)
Assessment for the purpose of monitoring change over time requires a different practical and statistical approach to that of assessment for diagnosing impairment. Sophisticated methods exist for identifying strengths and ...
Viability of Long-Term Gene Therapy in the Cochlea
(NATURE PUBLISHING GROUP, 2014-04-22)
Gene therapy has been investigated as a way to introduce a variety of genes to treat neurological disorders. An important clinical consideration is its long-term effectiveness. This research aims to study the long-term ...
Longitudinal change in dysarthria associated with Friedreich ataxia: a potential clinical endpoint
(SPRINGER HEIDELBERG, 2012-11-01)
CNS functions that show change across short periods of time are particularly useful clinical endpoints for Friedreich ataxia. This study determined whether there is measurable acoustical change in the dysarthria associated ...