Audiology and Speech Pathology - Research Publications
Now showing items 1-10 of 182
Can we detect altered disease state in early stage Huntington’s Disease using acoustic markers of speech?
(Causal Productions, 2012)
Altered prosody has been described in symptomatic Huntington’s Disease (HD) individuals, however, the extent to which acoustic analysis of speech is sensitive to gene positive pre-manifest (PreHD) individuals is unknown. ...
Acoustic analysis of the effects of 24 hours of sustained wakefulness
(Causal Productions, 2010)
The effect of 24 hours of sustained wakefulness on the speech of healthy adults is poorly documented. Therefore, speech samples were systematically acquired (e.g., every four hours) from 18 healthy adults over 24 hours. ...
Dysphagia and swallowing-related quality of life in Friedreich ataxia
Dysphagia in Friedreich ataxia (FRDA) and its impact on quality of life is not adequately understood. The objective of this study was to characterise dysphagia in FRDA and to determine the impact of swallowing dysfunction ...
Serum Methylarginines and Hearing Loss in a Population-based Cohort of Older Adults
(LIPPINCOTT WILLIAMS & WILKINS, 2018-04-01)
OBJECTIVE: Age-related hearing loss is associated with endothelial dysfunction and increased cardiovascular risk, suggesting a vascular etiology. Methylarginines are endogenous nitric oxide synthase inhibitors that cause ...
Tranilast administration reduces fibrosis and improves fatigue resistance in muscles of mdx dystrophic mice.
BACKGROUND: Duchenne muscular dystrophy (DMD) is a severe and progressive muscle-wasting disorder caused by mutations in the dystrophin gene that result in the absence of the membrane-stabilising protein dystrophin. ...
Phenotypic and Functional Characterization of Peripheral Sensory Neurons derived from Human Embryonic Stem Cells
(NATURE PUBLISHING GROUP, 2018-01-12)
The dorsal root ganglia (DRG) consist of a multitude of sensory neuronal subtypes that function to relay sensory stimuli, including temperature, pressure, pain and position to the central nervous system. Our knowledge of ...
Communication Outcomes for Groups of Children Using Cochlear Implants Enrolled in Auditory-Verbal, Aural-Oral, and Bilingual-Bicultural Early Intervention Programs
(LIPPINCOTT WILLIAMS & WILKINS, 2013-04-01)
OBJECTIVE: The relative impact of early intervention approach on speech perception and language skills was examined in these 3 well-matched groups of children using cochlear implants. STUDY DESIGN: Eight children from an ...
Can adolescents and young adults with prelingual hearing loss benefit from a second, sequential cochlear implant?
(TAYLOR & FRANCIS LTD, 2010-05-01)
This study aimed to determine if adolescents/young adults gained additional perceptual benefit from sequential bilateral cochlear implants within 12 months, and to document adaptation to the second implant. Assessments ...
Everyday Listening Performance of Children Before and After Receiving a Second Cochlear Implant: Results Using the Parent Version of the Speech, Spatial, and Qualities of Hearing Scale
(LIPPINCOTT WILLIAMS & WILKINS, 2016-01-01)
OBJECTIVES: To evaluate change in individual children's performance in general areas of everyday listening following sequential bilateral implantation, and to identify the specific types of listening scenarios in which ...