dc.contributor.author | Gc, VS | |
dc.contributor.author | Franklin, D | |
dc.contributor.author | Whitty, JA | |
dc.contributor.author | Dalziel, SR | |
dc.contributor.author | Babl, FE | |
dc.contributor.author | Schlapbach, LJ | |
dc.contributor.author | Fraser, JF | |
dc.contributor.author | Craig, S | |
dc.contributor.author | Neutze, J | |
dc.contributor.author | Oakley, E | |
dc.contributor.author | Schibler, A | |
dc.date.accessioned | 2020-12-14T05:58:42Z | |
dc.date.available | 2020-12-14T05:58:42Z | |
dc.date.issued | 2020-10-01 | |
dc.identifier | pii: archdischild-2019-318427 | |
dc.identifier.citation | Gc, V. S., Franklin, D., Whitty, J. A., Dalziel, S. R., Babl, F. E., Schlapbach, L. J., Fraser, J. F., Craig, S., Neutze, J., Oakley, E. & Schibler, A. (2020). First-line oxygen therapy with high-flow in bronchiolitis is not cost saving for the health service. ARCHIVES OF DISEASE IN CHILDHOOD, 105 (10), pp.975-980. https://doi.org/10.1136/archdischild-2019-318427. | |
dc.identifier.issn | 0003-9888 | |
dc.identifier.uri | http://hdl.handle.net/11343/254068 | |
dc.description.abstract | BACKGROUND: Bronchiolitis is the most common reason for hospital admission in infants. High-flow oxygen therapy has emerged as a new treatment; however, the cost-effectiveness of using it as first-line therapy is unknown. OBJECTIVE: To compare the cost of providing high-flow therapy as a first-line therapy compared with rescue therapy after failure of standard oxygen in the management of bronchiolitis. METHODS: A within-trial economic evaluation from the health service perspective using data from a multicentre randomised controlled trial for hypoxic infants (≤12 months) admitted to hospital with bronchiolitis in Australia and New Zealand. Intervention costs, length of hospital and intensive care stay and associated costs were compared for infants who received first-line treatment with high-flow therapy (early high-flow, n=739) or for infants who received standard oxygen and optional rescue high-flow (rescue high-flow, n=733). Costs were applied using Australian costing sources and are reported in 2016-2017 AU$. RESULTS: The incremental cost to avoid one treatment failure was AU$1778 (95% credible interval (CrI) 207 to 7096). Mean cost of bronchiolitis treatment including intervention costs and costs associated with length of stay was AU$420 (95% CrI -176 to 1002) higher per infant in the early high-flow group compared with the rescue high-flow group. There was an 8% (95% CrI 7.5 to 8.6) likelihood of the early high-flow oxygen therapy being cost saving. CONCLUSIONS: The use of high-flow oxygen as initial therapy for respiratory failure in infants with bronchiolitis is unlikely to be cost saving to the health system, compared with standard oxygen therapy with rescue high-flow. | |
dc.language | English | |
dc.publisher | BMJ PUBLISHING GROUP | |
dc.title | First-line oxygen therapy with high-flow in bronchiolitis is not cost saving for the health service | |
dc.type | Journal Article | |
dc.identifier.doi | 10.1136/archdischild-2019-318427 | |
melbourne.affiliation.department | Paediatrics (RCH) | |
melbourne.affiliation.department | | |
melbourne.source.title | Archives of Disease in Childhood | |
melbourne.source.volume | 105 | |
melbourne.source.issue | 10 | |
melbourne.source.pages | 975-980 | |
melbourne.elementsid | 1445576 | |
melbourne.openaccess.url | http://eprints.whiterose.ac.uk/159689/1/Gc_et_al_Archdischild_Manuscript_CleanCopy_for_pure.docx | |
melbourne.openaccess.status | Accepted version | |
melbourne.contributor.author | Babl, Franz | |
melbourne.contributor.author | Oakley, Edward | |
melbourne.contributor.author | Oakley, Edward | |
dc.identifier.eissn | 1468-2044 | |
melbourne.accessrights | Access this item via the Open Access location | |