Doxycycline and Sitafloxacin Combination Therapy for Treating Highly Resistant Mycoplasma genitalium

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    Author
    Durukan, D; Doyle, M; Murray, G; Bodiyabadu, K; Vodstrcil, L; Chow, EPF; Jensen, JS; Fairley, CK; Aguirre, I; Bradshaw, CS
    Date
    2020-08-01
    Source Title
    Emerging Infectious Diseases
    Publisher
    CENTERS DISEASE CONTROL & PREVENTION
    University of Melbourne Author/s
    Chow, Eric; Fairley, Christopher; Murray, Gerald
    Affiliation
    University General
    Obstetrics and Gynaecology
    Melbourne School of Population and Global Health
    Metadata
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    Document Type
    Journal Article
    Citations
    Durukan, D., Doyle, M., Murray, G., Bodiyabadu, K., Vodstrcil, L., Chow, E. P. F., Jensen, J. S., Fairley, C. K., Aguirre, I. & Bradshaw, C. S. (2020). Doxycycline and Sitafloxacin Combination Therapy for Treating Highly Resistant Mycoplasma genitalium. EMERGING INFECTIOUS DISEASES, 26 (8), pp.1870-1874. https://doi.org/10.3201/eid2608.191806.
    Access Status
    Access this item via the Open Access location
    URI
    http://hdl.handle.net/11343/254238
    DOI
    10.3201/eid2608.191806
    Open Access URL
    http://doi.org/10.3201/eid2608.191806
    Abstract
    Antimicrobial-resistant Mycoplasma genitalium is becoming increasingly common and creating major treatment challenges. We present early data on combination therapy with doxycycline and sitafloxacin to treat highly resistant M. genitalium. We found the regimen was well tolerated and cured 11/12 infections that had failed prior regimens with moxifloxacin and pristinamycin.

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