MLL-TFE3: a novel and aggressive KMT2A fusion identified in infant leukemia
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Kosasih, HJ; Davidson, NM; Bjelosevic, S; Morrish, E; Brennan, MS; Oshlack, A; Johnstone, RW; Brumatti, G; Khaw, SL; Ekert, PGDate
2020-10-13Source Title
Blood AdvancesPublisher
AMER SOC HEMATOLOGYAffiliation
Medical Biology (W.E.H.I.)Microbiology and Immunology
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Kosasih, H. J., Davidson, N. M., Bjelosevic, S., Morrish, E., Brennan, M. S., Oshlack, A., Johnstone, R. W., Brumatti, G., Khaw, S. L. & Ekert, P. G. (2020). MLL-TFE3: a novel and aggressive KMT2A fusion identified in infant leukemia. BLOOD ADVANCES, 4 (19), pp.4918-4923. https://doi.org/10.1182/bloodadvances.2020002708.Access Status
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http://doi.org/10.1182/bloodadvances.2020002708Abstract
<jats:title>Key Points</jats:title>
<jats:p>A novel KMT2A-rearrangement, MLL-TFE3, was identified in an infant leukemia patient. MLL-TFE3 expression produces aggressive leukemia in a mouse model.</jats:p>
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