Show simple item record

dc.contributor.authorChua, H-R
dc.contributor.authorMacLaren, G
dc.contributor.authorChoong, LH-L
dc.contributor.authorChionh, C-Y
dc.contributor.authorKhoo, BZE
dc.contributor.authorYeo, S-C
dc.contributor.authorSewa, D-W
dc.contributor.authorNg, S-Y
dc.contributor.authorChoo, JC-J
dc.contributor.authorTeo, B-W
dc.contributor.authorTan, H-K
dc.contributor.authorSiow, W-T
dc.contributor.authorAgrawal, RV
dc.contributor.authorTan, C-S
dc.contributor.authorVathsala, A
dc.contributor.authorTagore, R
dc.contributor.authorSeow, TY-Y
dc.contributor.authorKhatri, P
dc.contributor.authorHong, W-Z
dc.contributor.authorKaushik, M
dc.date.accessioned2020-12-16T23:44:32Z
dc.date.available2020-12-16T23:44:32Z
dc.date.issued2020-09-01
dc.identifierpii: S0272-6386(20)30730-7
dc.identifier.citationChua, H. -R., MacLaren, G., Choong, L. H. -L., Chionh, C. -Y., Khoo, B. Z. E., Yeo, S. -C., Sewa, D. -W., Ng, S. -Y., Choo, J. C. -J., Teo, B. -W., Tan, H. -K., Siow, W. -T., Agrawal, R. V., Tan, C. -S., Vathsala, A., Tagore, R., Seow, T. Y. -Y., Khatri, P., Hong, W. -Z. & Kaushik, M. (2020). Ensuring Sustainability of Continuous Kidney Replacement Therapy in the Face of Extraordinary Demand: Lessons From the COVID-19 Pandemic. AMERICAN JOURNAL OF KIDNEY DISEASES, 76 (3), pp.392-400. https://doi.org/10.1053/j.ajkd.2020.05.008.
dc.identifier.issn0272-6386
dc.identifier.urihttp://hdl.handle.net/11343/254509
dc.description.abstractWith the exponential surge in patients with coronavirus disease 2019 (COVID-19) worldwide, the resources needed to provide continuous kidney replacement therapy (CKRT) for patients with acute kidney injury or kidney failure may be threatened. This article summarizes subsisting strategies that can be implemented immediately. Pre-emptive weekly multicenter projections of CKRT demand based on evolving COVID-19 epidemiology and routine workload should be made. Corresponding consumables should be quantified and acquired, with diversification of sources from multiple vendors. Supply procurement should be stepped up accordingly so that a several-week stock is amassed, with administrative oversight to prevent disproportionate hoarding by institutions. Consumption of CKRT resources can be made more efficient by optimizing circuit anticoagulation to preserve filters, extending use of each vascular access, lowering blood flows to reduce citrate consumption, moderating the CKRT intensity to conserve fluids, or running accelerated KRT at higher clearance to treat more patients per machine. If logistically feasible, earlier transition to intermittent hemodialysis with online-generated dialysate, or urgent peritoneal dialysis in selected patients, may help reduce CKRT dependency. These measures, coupled to multicenter collaboration and a corresponding increase in trained medical and nursing staffing levels, may avoid downstream rationing of care and save lives during the peak of the pandemic.
dc.languageEnglish
dc.publisherW B SAUNDERS CO-ELSEVIER INC
dc.titleEnsuring Sustainability of Continuous Kidney Replacement Therapy in the Face of Extraordinary Demand: Lessons From the COVID-19 Pandemic
dc.typeJournal Article
dc.identifier.doi10.1053/j.ajkd.2020.05.008
melbourne.affiliation.departmentPaediatrics (RCH)
melbourne.source.titleAmerican Journal of Kidney Diseases
melbourne.source.volume76
melbourne.source.issue3
melbourne.source.pages392-400
melbourne.elementsid1456595
melbourne.openaccess.urlhttps://europepmc.org/articles/PMC7272152?pdf=render
melbourne.openaccess.statusPublished version
melbourne.contributor.authorMacLaren, Graeme
dc.identifier.eissn1523-6838
melbourne.accessrightsAccess this item via the Open Access location


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record