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dc.contributor.authorHowell, J
dc.contributor.authorPedrana, A
dc.contributor.authorSchroeder, SE
dc.contributor.authorScott, N
dc.contributor.authorAufegger, L
dc.contributor.authorAtun, R
dc.contributor.authorBaptista-Leite, R
dc.contributor.authorHirnschall, G
dc.contributor.author't Hoen, E
dc.contributor.authorHutchinson, SJ
dc.contributor.authorLazarus, J
dc.contributor.authorOlufunmilayo, L
dc.contributor.authorPeck, R
dc.contributor.authorSharma, M
dc.contributor.authorSohn, AH
dc.contributor.authorThompson, A
dc.contributor.authorThursz, M
dc.contributor.authorWilson, D
dc.contributor.authorHellard, M
dc.date.accessioned2020-12-16T23:48:09Z
dc.date.available2020-12-16T23:48:09Z
dc.date.issued2021-03-01
dc.identifierpii: S0168-8278(20)33625-4
dc.identifier.citationHowell, J., Pedrana, A., Schroeder, S. E., Scott, N., Aufegger, L., Atun, R., Baptista-Leite, R., Hirnschall, G., 't Hoen, E., Hutchinson, S. J., Lazarus, J., Olufunmilayo, L., Peck, R., Sharma, M., Sohn, A. H., Thompson, A., Thursz, M., Wilson, D. & Hellard, M. (2021). A global investment framework for the elimination of hepatitis B. JOURNAL OF HEPATOLOGY, 74 (3), pp.535-549. https://doi.org/10.1016/j.jhep.2020.09.013.
dc.identifier.issn0168-8278
dc.identifier.urihttp://hdl.handle.net/11343/254554
dc.description.abstractBACKGROUND & AIMS: More than 292 million people are living with hepatitis B worldwide and are at risk of death from cirrhosis and liver cancer. The World Health Organization (WHO) has set global targets for the elimination of viral hepatitis as a public health threat by 2030. However, current levels of global investment in viral hepatitis elimination programmes are insufficient to achieve these goals. METHODS: To catalyse political commitment and to encourage domestic and international financing, we used published modelling data and key stakeholder interviews to develop an investment framework to demonstrate the return on investment for viral hepatitis elimination. RESULTS: The framework utilises a public health approach to identify evidence-based national activities that reduce viral hepatitis-related morbidity and mortality, as well as international activities and critical enablers that allow countries to achieve maximum impact on health outcomes from their investments - in the context of the WHO's 2030 viral elimination targets. CONCLUSION: Focusing on hepatitis B, this health policy paper employs the investment framework to estimate the substantial economic benefits of investing in the elimination of hepatitis B and demonstrates how such investments could be cost saving by 2030. LAY SUMMARY: Hepatitis B infection is a major cause of death from liver disease and liver cancer globally. To reduce deaths from hepatitis B infection, we need more people to be tested and treated for hepatitis B. In this paper, we outline a framework of activities to reduce hepatitis B-related deaths and discuss ways in which governments could pay for them.
dc.languageEnglish
dc.publisherELSEVIER
dc.titleA global investment framework for the elimination of hepatitis B
dc.typeJournal Article
dc.identifier.doi10.1016/j.jhep.2020.09.013
melbourne.affiliation.departmentMedicine (St Vincent's)
melbourne.affiliation.departmentInfectious Diseases
melbourne.affiliation.facultyMedicine, Dentistry & Health Sciences
melbourne.source.titleJournal of Hepatology
melbourne.source.volume74
melbourne.source.issue3
melbourne.source.pages535-549
melbourne.identifier.nhmrc1142976
melbourne.elementsid1466338
melbourne.openaccess.urlhttps://europepmc.org/articles/PMC7505744?pdf=render
melbourne.openaccess.pmchttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505744
melbourne.openaccess.statusPublished version
melbourne.contributor.authorHellard, Margaret
melbourne.contributor.authorHowell, Jessica
melbourne.contributor.authorThompson, Alexander
dc.identifier.eissn1600-0641
melbourne.identifier.fundernameidNHMRC, 1142976
melbourne.accessrightsAccess this item via the Open Access location


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